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Titolo:
High risk genes predisposing to prostate cancer development - do they exist?
Autore:
Singh, R; Eeles, RA; Durocher, F; Simard, J; Edwards, S; Badzioch, M; Kote-Jarai, Z; Teare, D; Ford, D; Dearnaley, D; Ardern-Jones, A; Murkin, A; Dowe, A; Shearer, R; Kelly, J; Labrie, F; Easton, D; Narod, SA; Tonin, PN; Foulkes, WD;
Indirizzi:
Inst Canc Res, Sutton SMZ 5PT, Surrey, England Inst Canc Res Sutton Surrey England SMZ 5PT tton SMZ 5PT, Surrey, England Royal Marsden NHS Trust, Sutton, Surrey, England Royal Marsden NHS Trust Sutton Surrey England t, Sutton, Surrey, England CHUL, Res Ctr, Mol Endocrinol Lab, Quebec City, PQ, Canada CHUL Quebec City PQ Canada , Mol Endocrinol Lab, Quebec City, PQ, Canada Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA Univ Texas Houston TX USA 77030 Anderson Canc Ctr, Houston, TX 77030 USA Strangeways Res Lab, CRC, Genet Epidemiol Unit, Cambridge CB1 4RN, EnglandStrangeways Res Lab Cambridge England CB1 4RN Cambridge CB1 4RN, England Ctr Res Womens Hlth, Toronto, ON, Canada Ctr Res Womens Hlth Toronto ON Canada s Womens Hlth, Toronto, ON, Canada Montreal Gen Hosp, Dept Med, Montreal, PQ H3G 1A4, Canada Montreal Gen Hosp Montreal PQ Canada H3G 1A4 Montreal, PQ H3G 1A4, Canada
Titolo Testata:
PROSTATE CANCER AND PROSTATIC DISEASES
fascicolo: 4, volume: 3, anno: 2000,
pagine: 241 - 247
SICI:
1365-7852(2000)3:4<241:HRGPTP>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUSCEPTIBILITY LOCUS; BREAST-CANCER; LINKAGE ANALYSIS; CHROMOSOME 1Q42.2-43; STEROID 5-ALPHA-REDUCTASE; DOMINANT INHERITANCE; FAMILY HISTORY; UNITED-STATES; RELATIVES; BRCA2;
Keywords:
prostate cancer; genetics; high risk genes; low risk genes;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
68
Recensione:
Indirizzi per estratti:
Indirizzo: Singh, R Inst Canc Res, 15 Cotswold Rd, Sutton SMZ 5PT, Surrey, England Inst Canc Res 15 Cotswold Rd Sutton Surrey England SMZ 5PT ngland
Citazione:
R. Singh et al., "High risk genes predisposing to prostate cancer development - do they exist?", PROSTATE C, 3(4), 2000, pp. 241-247

Abstract

There is evidence for genetic predisposition to prostate cancer. However, prostate cancer genes have been more difficult to find than genes for some of the other common cancers, such as breast and colon cancer. The reasons for this are discussed in this article and it is now becoming clear that prostate cancer is probably due to multiple genes, many of which are moderate or low penetrance. The advances in the Human Genome Project and technology,especially that of robotics, will help to overcome these problems.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 07:08:04