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Titolo:
Volume-corrected mitotic index as a prognostic factor in oral squamous cell carcinomas
Autore:
Imai, Y; Sasaki, T; Fujibayashi, T;
Indirizzi:
Dokkyo Univ, Sch Med, Dept Oral & Maxillofacial Surg, Mibu, Tochigi 3210293, Japan Dokkyo Univ Mibu Tochigi Japan 3210293 Surg, Mibu, Tochigi 3210293, Japan
Titolo Testata:
ORAL ONCOLOGY
fascicolo: 1, volume: 37, anno: 2001,
pagine: 72 - 76
SICI:
1368-8375(200101)37:1<72:VMIAAP>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEAR MORPHOMETRIC VARIABLES; FLOW CYTOMETRIC DATA; HISTOQUANTITATIVE METHODS; BLADDER-CANCER; BREAST-CANCER; M/V-INDEX; PREDICTORS; MALIGNANCY;
Keywords:
oral squamous cell carcinoma; prognostic factor; volume-corrected mitotic index (M/V index);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Imai, Y Dokkyo Univ, Sch Med, Dept Oral & Maxillofacial Surg, 880 Kitakobayashi, Mibu, Tochigi 3210293, Japan Dokkyo Univ 880 Kitakobayashi Mibu Tochigi Japan 3210293 93, Japan
Citazione:
Y. Imai et al., "Volume-corrected mitotic index as a prognostic factor in oral squamous cell carcinomas", ORAL ONCOL, 37(1), 2001, pp. 72-76

Abstract

In order to predict the prognosis of patients with oral squamous cell carcinomas, volume-corrected mitotic index (M/V index), as well as histopathological and clinical indices were estimated in 50 oral squamous cell carcinoma tumors. Histological malignancy (P = 0.0005), mode of invasion (P = 0.0168) and M/V index (P = 0.0093) showed a significant correlation with survival according to univariate survival analysis. According to multivariate survival analysis (Cox's regression model), the M/V index was the best predictor of the techniques studied of patient prognosis. The M/V index also showedsignificant correlation with DNA ploidy. The present results suggest that the M/V index is an important prognostic factor for oral carcinoma. Furthermore, the M/V index and DNA ploidy appear to provide similar prognostic information. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 09:01:18