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Titolo:
Smoking and alcohol in the etiology of oral cancer: gender-specific risk profiles in the south of Greece
Autore:
Zavras, AI; Douglass, CW; Joshipura, K; Wu, T; Laskaris, G; Petridou, E; Dokianakis, G; Segas, J; Lefantzis, D; Nomikos, P; Wang, YF; Diehl, SR;
Indirizzi:
Natl Inst Dent & Craniofacial Res, Craniofacial Epidemiol & Genet Branch, Bethesda, MD 20892 USA Natl Inst Dent & Craniofacial Res Bethesda MD USA 20892 sda, MD 20892 USA Harvard Univ, Sch Dent Med, Dept Oral Hlth Policy & Epidemiol, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Policy & Epidemiol, Boston, MA 02115 USA Univ Athens, Sch Med, A Sygros Hosp, Dept Oral Med, GR-11527 Athens, Greece Univ Athens Athens Greece GR-11527 ept Oral Med, GR-11527 Athens, Greece Univ Athens, Sch Med, Dept Hyg & Epidemiol, GR-11527 Athens, Greece Univ Athens Athens Greece GR-11527 & Epidemiol, GR-11527 Athens, Greece Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 th, Dept Epidemiol, Boston, MA 02115 USA Red Cross Hosp Athens, ENT Clin, Athens, Greece Red Cross Hosp Athens Athens Greece sp Athens, ENT Clin, Athens, Greece Univ Athens, Sch Med, Dept Ear Nose & Throat, Athens 11528, Greece Univ Athens Athens Greece 11528 Ear Nose & Throat, Athens 11528, Greece Hippokratio Gen Hosp, Athens 11528, Greece Hippokratio Gen Hosp Athens Greece 11528 Gen Hosp, Athens 11528, Greece
Titolo Testata:
ORAL ONCOLOGY
fascicolo: 1, volume: 37, anno: 2001,
pagine: 28 - 35
SICI:
1368-8375(200101)37:1<28:SAAITE>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAVITY; CONSUMPTION; MORTALITY; DRINKING; TOBACCO; EUROPE;
Keywords:
mouth neoplasms; pharyngeal neoplasms; tobacco; smoking; alcohol; risk factors; women's health; Greece;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Diehl, SR Natl Inst Dent & Craniofacial Res, Craniofacial Epidemiol & Genet Branch, Bldg 45,Room 4as-43G, Bethesda, MD 20892 USA Natl Inst Dent & Craniofacial Res Bldg 45,Room 4as-43G Bethesda MD USA 20892
Citazione:
A.I. Zavras et al., "Smoking and alcohol in the etiology of oral cancer: gender-specific risk profiles in the south of Greece", ORAL ONCOL, 37(1), 2001, pp. 28-35

Abstract

Oral and pharyngeal cancer (OC) mortality is very low in Greece, especially among men, compared to other European countries. We conducted a case-control study of OC in Athens, and obtained information on tobacco, alcohol useand other potential risk factors and confounding variables for 110 incident cases and 115 hospital-based controls. We used multivariate logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Tobacco smoking (packyears, P-trend = 0.01) and alcohol use (drinks/week, P-trend = 0.07) were independent risk factors, with a multiplicative effect for combined exposures (OR, 8.3; 95% CI, 2.4 - 29.1. for > 28 alcohol drinks/week and > 50 packyears of cigarette smoking). The type of alcoholic beverage also seemed important: drinking ouzo and tsipouro (liquors of high ethanol concentration) was associated with greater increased OC risk than drinking comparable amounts of wine, beer or dark spirits. While alcohol drinkingis more common for male cases Versus controls, few men reported regularly consuming large quantities of ethanol associated with highest risk of OC inother studies. This may partially explain the low rates of male OC mortality in Greece. Among the 38% of our cases who were women, however, neither smoking nor alcohol drinking frequencies were significantly elevated compared to controls, and so the etiology of OC risk in females requires further investigation, (C) Published by Elsevier Science Ltd.

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Documento generato il 26/01/20 alle ore 16:09:18