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Titolo:
Peripheral ameloblastoma: biological profile based on 160 cases from the literature
Autore:
Philipsen, HP; Reichart, PA; Nikai, H; Takata, T; Kudo, Y;
Indirizzi:
Humboldt Univ, Ctr Oral Med, Dept Oral Surg & Dent Radiol, D-13353 Berlin,Germany Humboldt Univ Berlin Germany D-13353 Dent Radiol, D-13353 Berlin,Germany Hiroshima Univ, Sch Dent, Dept Oral Pathol, Hiroshima, Japan Hiroshima Univ Hiroshima Japan Dent, Dept Oral Pathol, Hiroshima, Japan
Titolo Testata:
ORAL ONCOLOGY
fascicolo: 1, volume: 37, anno: 2001,
pagine: 17 - 27
SICI:
1368-8375(200101)37:1<17:PABPBO>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
BASAL-CELL-CARCINOMA; ODONTOGENIC EPITHELIAL HAMARTOMA; BUCCAL MUCOSA; GINGIVA; NEOPLASM; TUMORS; FIBROMA; LIGHT;
Keywords:
peripheral ameloblastoma; odontogenic tumour; jaws; tumour profile;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
156
Recensione:
Indirizzi per estratti:
Indirizzo: Reichart, PA Humboldt Univ, Ctr Oral Med, Dept Oral Surg & Dent Radiol, D-13353 Berlin,Germany Humboldt Univ Berlin Germany D-13353 D-13353 Berlin,Germany
Citazione:
H.P. Philipsen et al., "Peripheral ameloblastoma: biological profile based on 160 cases from the literature", ORAL ONCOL, 37(1), 2001, pp. 17-27

Abstract

The present profile of the peripheral ameloblastoma (PA) is based on a literature survey of 160 published tumour cases. The PA is an exophytic growthlocalized to the soft tissues overlying the tooth-bearing areas of the jaws, the initial diagnosis often being fibrous epulis. In most cases there isno radiological evidence of bone involvement, but a superficial bone erosion - known as cupping or saucerization - may be detected at operation. The PA accounts for 2 - 10% of all ameloblastomas. The overall average age is 52.1 years, slightly higher for males (52.9 years) than for females (50.6 years). Thus, the PA occurs at a significantly higher age than the intraosseous ameloblastoma (IA; 37.4 years). The male/female ratio amounts to 1.9.1, as opposed to 1.2:1 for the IA. The male/female ratio for the Japanese cases included in this survey is 2.5:1 as opposed to that of non-Japanese cases1.4.1. As to the location of PA, the maxilla/mandible ratio is 1:2.6. The mandibular premolar region accounts for 32.6% of all sites. Five extra-gingival lesions have been reported under the term PA. As these cases most likely represent salivary gland tumours, they are not accepted under the diagnosis of PA. The odontogenic gingival epithelial hamartoma shows clinical, histological and behavioural features almost identical to the PA, and it is discussed whether this lesion and the PA should be considered one and the same entity. Pathogenetically, two major sources are discussed: remnants of the dental lamina and the oral surface epithelium. Histologically, the PA consists of proliferating odontogenic epithelium exhibiting the same histomorphological cell types and patterns as seen in the IA. The stroma is that ofa mature, fibrous connective tissue. The indolent biological behaviour dictates a conservative therapeutical approach. It is discussed whether PA is a true neoplastic counterpart of the IA or rather an odontogenic hamartomatous lesion. Six cases of malignant PA have been reported. (C) 2001 ElsevierScience Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 10:20:13