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Titolo:
Neurological soft signs in schizophrenic patients: Influence of age, age at onset, sex, and family history of schizophrenia
Autore:
Bjorck, RV; Sjalin, M; Nordin, C;
Indirizzi:
Karolinska Inst, Karolinska Hosp, Psychiat Sect, Dept Clin Neurosci, SE-17176 Stockholm, Sweden Karolinska Inst Stockholm Sweden SE-17176 ci, SE-17176 Stockholm, Sweden Linkoping Univ Hosp, Div Psychiat, Dept Neurosci & Locomot, SE-58185 Linkoping, Sweden Linkoping Univ Hosp Linkoping Sweden SE-58185 SE-58185 Linkoping, Sweden
Titolo Testata:
NORDIC JOURNAL OF PSYCHIATRY
fascicolo: 6, volume: 54, anno: 2000,
pagine: 437 - 440
SICI:
0803-9488(2000)54:6<437:NSSISP>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROPSYCHOLOGICAL IMPAIRMENTS; ABNORMALITIES; NEUROMOTOR; NAIVE;
Keywords:
age; age at onset; neurological soft signs; schizophrenia; sex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Bjorck, RV Huddinge Univ Hosp, Psychiat Sect, Dept Clin Neurosci Occupat Therapy & Elderly Care, SE-14186 Huddinge, Sweden Huddinge Univ Hosp Huddinge Sweden SE-14186 Huddinge, Sweden
Citazione:
R.V. Bjorck et al., "Neurological soft signs in schizophrenic patients: Influence of age, age at onset, sex, and family history of schizophrenia", NORD J PSY, 54(6), 2000, pp. 437-440

Abstract

Neurological soft signs (NSS) are indicators of subtle neurodysfunction which are overrepresented in schizophrenics. The issue of the significance ofNSS is still unclear in spite of a considerable amount of literature on the subject. The objective of this study was to investigate the impact on NSSof genetic and environmental factors presumed to be relevant to the etiology and prognosis of schizophrenia. Data on NSS (using a slightly modified version of the Neurological Evaluation Scale) and the age, age at onset, sexand family history of schizophrenia of 50 schizophrenic patients were collected. Extrapyramidal signs were measured with the Extrapyramidal Symptoms Rating Scale. Backward regression analyses with two-factor interactions regression were used to evaluate the influence of the variables on the NSS total score, subscores, and single items. Age at onset and the age-age at onset interaction influenced co-ordination tasks. Sex and the interaction between age and sex influenced sequencing tasks, with males having higher and females lower scores with increasing age. None of the other variables influenced the NSS total score or subscores. Schizophrenics with early onset of disease may perform worse than late-onset patients in motor co-ordination tasks at the onset, but the age-dependent deterioration of motor co-ordinationmay be more rapid in late-onset patients. Performance in sequencing tasks may be influenced by sex-bound variables.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:29:27