Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Role of cholinergic mossy fibers in medial vestibular and prepositus hypoglossal nuclei in vestibular compensation
Autore:
Fukushima, M; Kitahara, T; Takeda, N; Saika, T; Uno, A; Kubo, T;
Indirizzi:
Osaka Univ, Sch Med, Dept Otolaryngol, Osaka 5650871, Japan Osaka Univ Osaka Japan 5650871 d, Dept Otolaryngol, Osaka 5650871, Japan
Titolo Testata:
NEUROSCIENCE
fascicolo: 1, volume: 102, anno: 2001,
pagine: 159 - 166
SICI:
0306-4522(2001)102:1<159:ROCMFI>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT BRAIN-STEM; UNILATERAL LABYRINTHECTOMY; FOS EXPRESSION; NITRIC-OXIDE; FLOCCULUS; RETROGRADE;
Keywords:
Fos; acetylcholine; ethylcholine mustard aziridinium ion (AF64A); fluoro-gold dye; flocculus; uvula-nodulus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Kitahara, T Osaka Univ, Sch Med, Dept Otolaryngol, 2-2 Yamadaoka, Osaka 5650871, Japan Osaka Univ 2-2 Yamadaoka Osaka Japan 5650871 a 5650871, Japan
Citazione:
M. Fukushima et al., "Role of cholinergic mossy fibers in medial vestibular and prepositus hypoglossal nuclei in vestibular compensation", NEUROSCIENC, 102(1), 2001, pp. 159-166

Abstract

Several lines of evidence have suggested that acetylcholine is a possible neurotransmitter/neuromodulator involved in vestibular compensation. Further, the central vestibular system, oculo- and spine-motor neurons and peripheral vestibular efferents contain abundant cholinergic neurons. However, details of cholinergic effective sites during vestibular compensation remain to be clarified. In the present study, we selectively damaged rat vestibulo-floccular and vestibulo-uvulonodular cholinergic mossy fibers using ethylcholine mustard aziridinium ions. In these treated animals, unilateral labyrinthectomy caused more severe vestibule-ocular deficits especially during the initial stage. From these findings we suggest that vestibulo-floccular and vestibulo-uvulonodular cholinergic mossy fibers contribute to the restoration of a balance between intervestibular nuclear activities for the induction of vestibular compensation during the initial stage. (C) 2001 IBRO. Published by Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 13:40:57