Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Expression of neural cell adhesion molecule in spinal cords following a complete transection
Autore:
Tzeng, SF; Cheng, H; Lee, YS; Wu, JP; Hoffer, BJ; Kuo, JS;
Indirizzi:
Taichung Vet Gen Hosp, Dept Res & Educ, Taichung 40705, Taiwan Taichung Vet Gen Hosp Taichung Taiwan 40705 Educ, Taichung 40705, Taiwan Vet Gen Hosp, Inst Neurol, Neural Regenerat Lab, Taipei, Taiwan Vet Gen Hosp Taipei Taiwan Neurol, Neural Regenerat Lab, Taipei, Taiwan NIDA, NIH, Baltimore, MD 21224 USA NIDA Baltimore MD USA 21224NIDA, NIH, Baltimore, MD 21224 USA
Titolo Testata:
LIFE SCIENCES
fascicolo: 9, volume: 68, anno: 2001,
pagine: 1005 - 1012
SICI:
0024-3205(20010119)68:9<1005:EONCAM>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADULT PARAPLEGIC RATS; MOUSE SCIATIC-NERVE; N-CAM; RECOGNITION MOLECULES; NCAM; L1; SCHIZOPHRENIA; HIPPOCAMPUS; REGENERATION; ZEBRAFISH;
Keywords:
neural cellular adhesion molecule (NCAM); glia; spinal cord injury; neuronal regeneration;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Tzeng, SF Taichung Vet Gen Hosp, Dept Res & Educ, 160 Sec,3 Taichung Kang Rd, Taichung 40705, Taiwan Taichung Vet Gen Hosp 160 Sec,3 Taichung Kang RdTaichung Taiwan 40705
Citazione:
S.F. Tzeng et al., "Expression of neural cell adhesion molecule in spinal cords following a complete transection", LIFE SCI, 68(9), 2001, pp. 1005-1012

Abstract

Neural cell adhesion molecule (NCAM) regulates tissue organization during development and in the adult. NCAM upregulation occurs after an injury to brains and sciatic nerves. However, little is known about NCAM expression after spinal cord injury (SCI). By using a complete spinal cord transection with a 5 mm tissue removal, an increase in the NCAM level is detected in spinal cord stumps proximal and distal to the transection site at 1 d and 3 d post injury, while its expression at 8 d is declined to a lower level than that observed in sham-operated spinal cords. The strong NCAM expression is present in motor neurons at 3 d post transection whereas the intensive NCAMimmunostaining is localized in dorsal sensory and corticospinal fiber tracts at 8 d following injury. Collectively, NCAM level is elevated and strongly expressed in dorsal fiber tracts after SCI, implying that the endogenousprocess for spinal cord regeneration may take place after SCI. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 06:08:03