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Titolo:
Prevalence and correlates of anemia in a large cohort of HIV-infected women: Women's interagency HIV study
Autore:
Levine, AM; Berhane, K; Masri-Lavine, L; Sanchez, ML; Young, M; Augenbraun, M; Cohen, M; Anastos, K; Newman, M; Gange, SJ; Watts, H;
Indirizzi:
Univ So Calif, Sch Med, Los Angeles, CA USA Univ So Calif Los Angeles CA USA So Calif, Sch Med, Los Angeles, CA USA Georgetown Univ, Washington, DC USA Georgetown Univ Washington DC USAGeorgetown Univ, Washington, DC USA Maimonides Med Ctr, Brooklyn, NY 11219 USA Maimonides Med Ctr Brooklyn NYUSA 11219 Med Ctr, Brooklyn, NY 11219 USA Cook Cty Hosp, Chicago, IL 60612 USA Cook Cty Hosp Chicago IL USA 60612Cook Cty Hosp, Chicago, IL 60612 USA Albert Einstein Coll Med, Bronx, NY 10467 USA Albert Einstein Coll Med Bronx NY USA 10467 Coll Med, Bronx, NY 10467 USA Univ Calif San Francisco, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Johns Hopkins Sch Hyg & Publ Hlth, Baltimore, MD USA Johns Hopkins Sch Hyg& Publ Hlth Baltimore MD USA th, Baltimore, MD USA NIH, Rockville, MD USA NIH Rockville MD USANIH, Rockville, MD USA
Titolo Testata:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
fascicolo: 1, volume: 26, anno: 2001,
pagine: 28 - 35
SICI:
1525-4135(20010101)26:1<28:PACOAI>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNODEFICIENCY-VIRUS INFECTION; UNITED-STATES; WHITE WOMEN; ERYTHROPOIETIN; BLACK; AIDS; EPIDEMIOLOGY; THALASSEMIA; SURVIVAL;
Keywords:
HIV; anemia; women;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Levine, AM Univ So Calif, Norris Canc Hosp, 1441 Eastlake Ave,MS 34, Los Angeles, CA 90033 USA Univ So Calif 1441 Eastlake Ave,MS 34 Los Angeles CA USA 90033
Citazione:
A.M. Levine et al., "Prevalence and correlates of anemia in a large cohort of HIV-infected women: Women's interagency HIV study", J ACQ IMM D, 26(1), 2001, pp. 28-35

Abstract

Anemia is a common manifestation of HIV infection, occurring in aproximately 30% of patients with asymptomatic infection and in as many as 75% to 80%of those with AIDS. Anemia has been associated with decreased quality of life and decreased survival. We performed a cross-sectional study nested within a multicenter prospective cohort study to describe the prevalence of anemia in 2056 HIV-infected and 569 HIV-negative women as well as to define the demographic, clinical, immunologic, and virologic correlates of anemia among HIV-infected women. A total of 37% of HIV-positive women and 17% of HIV-negative women had hemoglobin levels < 12 g/dl (p <.001). Factors associated with anemia in HIV-positive and HIV-negative women included mean corpuscular volume (MCV) < <80 fl (p < .001) and black race (p <.001). Among HIV-infected women, multivariate logistic analyses revealed that African American race (p < .0001), MCV < 80 fl (p < .0001), CD3 count < 200 per microliter (p < .0001), higher HIV RNA in plasma (p = .02), current use of ZDV (p = .01), and history of clinical AIDS (p = .004) were all independent predictors of anemia. These data indicate that worsening parameters of HIV disease are associated with anemia among HIV-infected women. Black women and women with Low MCV values are at increased risk for anemia independent of HIV status.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 15:53:54