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Titolo:
Iron stores in multi-transfused thalassaemic patients seem not to be influenced by the HLA system
Autore:
Konstantopoulos, K; Theocharis, S; Karagiorga, M; Rombos, Y; Youssef, J; Karabatsos, F; Sourdis, J;
Indirizzi:
Univ Athens, Laikon Hosp, Sch Med, Thalassaemia Clin,Dept Med 1, Athens 11527, Greece Univ Athens Athens Greece 11527 ia Clin,Dept Med 1, Athens 11527, Greece
Titolo Testata:
HAEMATOLOGIA
fascicolo: 4, volume: 30, anno: 2000,
pagine: 319 - 323
SICI:
0017-6559(2000)30:4<319:ISIMTP>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
THALASSEMIA MINOR; HEMOCHROMATOSIS; OVERLOAD; ANTIGENS; MALARIA;
Keywords:
Thalassaemia; iron; siderosis; HLA antigens;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Konstantopoulos, K Univ Athens, Laikon Hosp, Sch Med, Thalassaemia Clin,Dept Med 1, Athens 11527, Greece Univ Athens Athens Greece 11527 Athens 11527, Greece
Citazione:
K. Konstantopoulos et al., "Iron stores in multi-transfused thalassaemic patients seem not to be influenced by the HLA system", HAEMATOLOGI, 30(4), 2000, pp. 319-323

Abstract

The HLA-A and -B antigens of 99 Greek patients with transfusion dependent homozygous beta thalassaemia were determined. The HLA antigen distribution in thalassaemic patients with a severe transfusion siderosis and in patients without signs of siderosis were compared to that of 400 healthy unrelatedcontrols from the same population. There is an increase of HLA-B14 antigenin both groups of thalassaemics as compared with the controls. No significant difference exists in the distribution of all the other HLA antigens between the two sub-groups of thalassaemics or with the controls.

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Documento generato il 04/04/20 alle ore 12:14:26