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Titolo:
Endoscopic screening for early esophageal cancer by iodine staining in patients with other current or prior primary cancers
Autore:
Shimizu, Y; Tukagoshi, H; Fujita, M; Hosokawa, M; Kato, M; Asaka, M;
Indirizzi:
Keiyukai Sapporo Hosp, Dept Internal Med, Sapporo, Hokkaido 0030027, JapanKeiyukai Sapporo Hosp Sapporo Hokkaido Japan 0030027 kaido 0030027, Japan Keiyukai Sapporo Hosp, Dept Pathol, Sapporo, Hokkaido 0030027, Japan Keiyukai Sapporo Hosp Sapporo Hokkaido Japan 0030027 kaido 0030027, Japan Keiyukai Sapporo Hosp, Dept Surg, Sapporo, Hokkaido 0030027, Japan Keiyukai Sapporo Hosp Sapporo Hokkaido Japan 0030027 kaido 0030027, Japan Hokkaido Univ, Sch Med, Div Endoscopy, Sapporo, Hokkaido 060, Japan Hokkaido Univ Sapporo Hokkaido Japan 060 py, Sapporo, Hokkaido 060, Japan Hokkaido Univ, Sch Med, Dept Internal Med 3, Sapporo, Hokkaido 060, Japan Hokkaido Univ Sapporo Hokkaido Japan 060 3, Sapporo, Hokkaido 060, Japan
Titolo Testata:
GASTROINTESTINAL ENDOSCOPY
fascicolo: 1, volume: 53, anno: 2001,
pagine: 1 - 5
SICI:
0016-5107(200101)53:1<1:ESFEEC>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE PRIMARY CANCERS; SQUAMOUS-CELL CARCINOMA; AERODIGESTIVE TRACT; ALCOHOL-CONSUMPTION; REPLICATION ERRORS; GASTRIC-CANCER; TUMORS; TOBACCO; JAPAN; HEAD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Shimizu, Y Keiyukai Sapporo Hosp, Dept Internal Med, Hondori 14 Chome Kita1-1, Sapporo, Hokkaido 0030027, Japan Keiyukai Sapporo Hosp Hondori 14 Chome Kita 1-1 Sapporo Hokkaido Japan 0030027
Citazione:
Y. Shimizu et al., "Endoscopic screening for early esophageal cancer by iodine staining in patients with other current or prior primary cancers", GASTROIN EN, 53(1), 2001, pp. 1-5

Abstract

Background: Although early diagnosis of esophageal carcinoma is an important determinant of outcome, early stage carcinomas are rarely detected on routine endoscopic examination, iodine staining may be useful in the detection of early stage esophageal carcinoma, especially in highrisk populations. In a prior study, 29.2% (68/233) patients with superficial esophageal carcinoma (SEC) undergoing resection at our hospital had other nonesophageal primary carcinomas, suggesting that patients with nonesophageal primary cancers are at increased risk for the development of esophageal cancer. The aim of the current study was to determine whether endoscopic screening with iodine staining is useful for the detection of SEC in patients with a history of nonesophageal cancers. Patients and methods: In a prospective study, 331 patients with nonesophageal primary cancers were screened for esophageal cancer by endoscopic examination with iodine staining. All patients were men 55 years of age or older. Results: Nine patients (2.7%) with SEC were identified, Among these patients, 7 with mucosal cancer were treated by endoscopic mucosal resection, and2 with submucosal cancer were treated by surgical resection or radiation therapy. Five patients (1.5%) were found to have cancer confined to the epithelium or the lamina propria. These lesions were difficult to detect by conventional endoscopic screening and were cured by endoscopic mucosal resection. After exclusion of 51 patients with head and neck cancer, the incidenceof SEC was still 2.1% (6/280), higher than reported in prior screening studies. Conclusions: All men with a history of nonesophageal primary cancers should undergo endoscopic screening for esophageal cancer. Endoscopic iodine staining in such patients may be useful in screening for early stage esophageal carcinoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 15:03:18