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Titolo:
New horizons in cytoskeletal dynamics: transport of intermediate filamentsalong microtubule tracks
Autore:
Chou, YH; Helfand, BT; Goldman, RD;
Indirizzi:
Northwestern Univ, Sch Med, Dept Cell & Mol Biol, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 & Mol Biol, Chicago, IL 60611 USA
Titolo Testata:
CURRENT OPINION IN CELL BIOLOGY
fascicolo: 1, volume: 13, anno: 2001,
pagine: 106 - 109
SICI:
0955-0674(200102)13:1<106:NHICDT>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
SLOW AXONAL-TRANSPORT; NEUROFILAMENTS; SUBUNIT; PHOSPHORYLATION; VIMENTIN; NETWORKS; TUBULIN; KINASE; MODEL; CELLS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Goldman, RD Northwestern Univ, Sch Med, Dept Cell & Mol Biol, 303 E Chicago Ave, Chicago, IL 60611 USA Northwestern Univ 303 E Chicago Ave Chicago ILUSA 60611 1 USA
Citazione:
Y.H. Chou et al., "New horizons in cytoskeletal dynamics: transport of intermediate filamentsalong microtubule tracks", CURR OP CEL, 13(1), 2001, pp. 106-109

Abstract

Until recently, the dynamic properties of intermediate filaments (IF) wereattributed primarily to the exchange of subunits between a disassembled pool and polymerized 10 nm filaments. During interphase, this subunit exchange process was thought to produce local modifications in IF structure. During cell division, shifts in the equilibrium between subunits and polymers were thought to lead to either the global or regional disassembly of IF networks, thereby facilitating their distribution into daughter cells. Recently,novel structural forms of IF that undergo rapid and directed transport in several cell types were revealed. Time-lapse observations of motile IF structures in different cell systems have also revealed novel insights into themechanisms underlying the transport of cytoskeletal components throughout the cytoplasm and the molecular basis of the 'crosstalk' between different cytoskeletal systems.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:44:27