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Titolo:
Comparative study of home and office blood pressure in hypertensive patients treated with enalapril/HCTZ 20/6 mg: The ESPADA study
Autore:
Campo, C; Fernandez, G; Gonzalez-Esteban, J; Segura, J; Ruilope, LM;
Indirizzi:
Hosp 12 Octubre, Hypertens Unit, ES-28041 Madrid, Spain Hosp 12 Octubre Madrid Spain ES-28041 rtens Unit, ES-28041 Madrid, Spain Merck Sharp & Dohme Espana, Dept Clin Res, Madrid, Spain Merck Sharp & Dohme Espana Madrid Spain a, Dept Clin Res, Madrid, Spain
Titolo Testata:
BLOOD PRESSURE
fascicolo: 6, volume: 9, anno: 2000,
pagine: 355 - 362
SICI:
0803-7051(2000)9:6<355:CSOHAO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
MILD HYPERTENSION;
Keywords:
ACE inhibitors; essential hypertension; home blood pressure; office blood pressure; low-dose diuretic combination;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Campo, C Hosp 12 Octubre, Hypertens Unit, Avda Cordoba S-N, ES-28041 Madrid, Spain Hosp 12 Octubre Avda Cordoba S-N Madrid Spain ES-28041 id, Spain
Citazione:
C. Campo et al., "Comparative study of home and office blood pressure in hypertensive patients treated with enalapril/HCTZ 20/6 mg: The ESPADA study", BLOOD PRESS, 9(6), 2000, pp. 355-362

Abstract

The introduction and generalization of 24-h ambulatory blood pressure (BP)monitoring has shown the clinical relevance of home BP. The aim of this study was to assess the validity of home-measured BP for monitoring and controlling patients with arterial hypertension while on a homogeneous treatment. An additional objective was to establish the degree of office BP control obtained. This was a prospective, longitudinal, observational and multicenter study in a cohort of 156 patients of both sexes, aged over 18 years and with essential hypertension. All of them received the fixed combination enalapril/HCTZ 20/6 mg as the only hypertensive agent for at least 4 weeks previously. Office BP was the average of three measurements. For home BP, a semi-automated device (OMRON HEM 705 CP) was used. The patients measured their BP twice a day for 2 consecutive days. The average differences between the two measuring methods were low, but significant: 3.99 mmHg for systolic BP (SBP; p < 0.05), 2.02 mmHg for diastolic BP (DBP; p < 0.05). Pearson's regression coefficient between the office and home values was highly significant (p < 0.0001) for SBP, DBP and heart rate. Home BP measurement was highly reproducible as shown by the high within-class correlation coefficient for individual measurements on the first day compared with the second: 0.88 (95% confidence interval, CI 0.82-0.92; p < 0.00001) for SBP and 0.89 for DBP (95% CI 0.83-0.93; p < 0.00001). The percentage of patients with strict office DBP and SBP control (<140/90 mmHg) was 61.3% and with DBP control (<90 mmHg) 92%. In conclusion, in the ESPADA study, the application of home BPmeasurement is valid, reproducible and shows a high correlation with office BP.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 15:34:35