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Titolo:
A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group
Autore:
Lance, RS; Freidrichs, PA; Kane, C; Powell, CR; Pulos, E; Moul, JW; McLeod, DG; Cornum, RL; Thrasher, JB;
Indirizzi:
Madigan Army Med Ctr, Dept Surg, Serv Urol, Tacoma, WA 98431 USA Madigan Army Med Ctr Tacoma WA USA 98431 Serv Urol, Tacoma, WA 98431 USA Wilford Hall USAF Med Ctr, San Antonio, TX 78236 USA Wilford Hall USAF MedCtr San Antonio TX USA 78236 Antonio, TX 78236 USA Brooke Army Med Ctr, San Antonio, TX USA Brooke Army Med Ctr San Antonio TX USA Army Med Ctr, San Antonio, TX USA USN, San Diego Med Ctr, San Diego, CA 92152 USA USN San Diego CA USA 92152 SN, San Diego Med Ctr, San Diego, CA 92152 USA Walter Reed Army Med Ctr, Washington, DC 20307 USA Walter Reed Army Med Ctr Washington DC USA 20307 Washington, DC 20307 USA
Titolo Testata:
BJU INTERNATIONAL
fascicolo: 1, volume: 87, anno: 2001,
pagine: 61 - 65
SICI:
1464-4096(200101)87:1<61:ACORRW>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
MARGINS;
Keywords:
prostatectomy; retropubic; perineal; outcome;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Lance, RS Madigan Army Med Ctr, Dept Surg, Serv Urol, Tacoma, WA 98431 USAMadigan Army Med Ctr Tacoma WA USA 98431 , Tacoma, WA 98431 USA
Citazione:
R.S. Lance et al., "A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group", BJU INT, 87(1), 2001, pp. 61-65

Abstract

Objective To review and compare the outcome of patients undergoing radicalretropubic prostatectomy (RRP) or radical perineal prostatectomy (RPP) forclinically localized prostate cancer,Patients and methods From 1988 to 1997, 1382 men who were treated by RRP and 316 by RPP were identified from databases of the Uniformed Services Urology Research Group. The following variables were assessed; age, race, prostate-specific antigen (PSA) level before surgery, clinical stage, biopsy Gleason sum, estimated blood loss (EBL), margin-positive rate, pathological stage, biochemical recurrence rate, short and long-term complication rates, impotence and incontinence rates. To eliminate selection bias, the analysis was concentrated on pairs of patients matched by race, preoperative PSA level, clinical stage and biopsy Gleason sum. Results In the 190 matched patients there were no significant differences between the RRP and RPP groups in either organ-confined (57% vs 55%), margin-positive (39% vs 43%), or biochemical recurrence rates (12.9% vs 17.6% ata mean followup of 47.1 vs 42.9 months), respectively. The mean EEL was 1575 mi, in the RRP group and 802 mt in the RPP group (P < 0.001). The only significant difference in complication rates was a higher incidence of rectal injury in the RPP group (4.9%) than in the RRP group (none, P < 0.05). Conclusions In similar populations of patients, RPP offers equivalent organ-confirmed, margin-positive and biochemical recurrence rates to RRP, whilecausing significantly less blood loss.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:15:31