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Titolo:
Sustained anxiety and 4-year progression of carotid atherosclerosis
Autore:
Paterniti, S; Zureik, M; Ducimetiere, P; Touboul, PJ; Feve, JM; Alperovitch, A;
Indirizzi:
INSERM, U360, Nantes, France INSERM Nantes FranceINSERM, U360, Nantes, France INSERM, U258, Nantes, France INSERM Nantes FranceINSERM, U258, Nantes, France INSERM, Ctr Diagnost & Prevent Neurovasc, Nantes, France INSERM Nantes France , Ctr Diagnost & Prevent Neurovasc, Nantes, France INSERM, Ctr Examen EVA, Nantes, France INSERM Nantes FranceINSERM, Ctr Examen EVA, Nantes, France
Titolo Testata:
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
fascicolo: 1, volume: 21, anno: 2001,
pagine: 136 - 141
SICI:
1079-5642(200101)21:1<136:SAA4PO>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISCHEMIC-HEART-DISEASE; CORONARY-ARTERY DISEASE; INTIMA-MEDIA THICKNESS; A BEHAVIOR PATTERN; BLOOD-PRESSURE; MYOCARDIAL-INFARCTION; PHOBIC ANXIETY; CARDIOVASCULAR MORTALITY; BAROREFLEX SENSITIVITY; RATE-VARIABILITY;
Keywords:
trait anxiety; carotid arteries; atherosclerosis; longitudinal studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Paterniti, S Hop La Pitie Salpetriere, INSERM, U360, 84 Bd Hop, F-75651 Paris 13, France Hop La Pitie Salpetriere 84 Bd Hop Paris France 13 3, France
Citazione:
S. Paterniti et al., "Sustained anxiety and 4-year progression of carotid atherosclerosis", ART THROM V, 21(1), 2001, pp. 136-141

Abstract

Several studies have shown that anxiety disorders are associated with a higher risk of coronary artery disease. However, the relationship between anxiety disorders and atherosclerosis has been studied to a lesser extent. Thegoal of this study was to examine whether high and stable trait anxiety was associated with the progression of atherosclerosis, The study group consisted of 726 subjects (297 men and 429 women), aged 59 to 71 years, recruited from the electoral rolls of the city of Nantes. The subjects had no history of coronary artery disease at baseline evaluation and or at the 2-year follow-up. Two follow-up examinations were conducted 2 and 4 years after thebaseline evaluation. Trait anxiety was evaluated by means of the French translation of the Spielberger Inventory (a 20-item trait inventory, form X-2). The "sustained anxiety" group consisted of men and women with the highest Spielberger Inventory scores at baseline and at the 2-year follow-up examination. Each ultrasound examination included measurement of intima-media thickness and the sites of plaque in the extracranial carotid arteries. Men with sustained anxiety showed a higher 4-year increase of common carotid intima-media thickness than did men without sustained anxiety (adjusted means0.08 versus 0.04 mm, respectively; P=0.05) and a higher risk of 4-year plaque occurrence (adjusted OR 3.5, 95% CI 1.4 to 8.5). Among women, sustainedanxiety was associated with a higher 4-year increase of common carotid intima-media thickness (0.07 versus 0.04 for women with versus women without sustained anxiety, respectively; P=0.07), These results suggest that chronically high levels of anxiety may contribute to accelerating the evolution ofcarotid atherosclerosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 06:21:38