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Titolo:
Clinical significance of ventilation/perfusion scans in collagen disease patients
Autore:
Suzuki, K; Kamata, N; Inokuma, S; Terada, H; Yokoyama, Y; Abe, K; Mochizuki, T; Kobayashi, T;
Indirizzi:
Tokyo Metropolitan Hiro O Hosp, Dept Radiol, Shibuya Ku, Tokyo 1500013, Japan Tokyo Metropolitan Hiro O Hosp Tokyo Japan 1500013 Tokyo 1500013, Japan Tokyo Metrolpolitan Komagome Hosp, Dept Radiol, Tokyo, Japan Tokyo Metrolpolitan Komagome Hosp Tokyo Japan Dept Radiol, Tokyo, Japan Tokyo Metrolpolitan Komagome Hosp, Dept Internal Med, Tokyo, Japan Tokyo Metrolpolitan Komagome Hosp Tokyo Japan nternal Med, Tokyo, Japan
Titolo Testata:
ANNALS OF NUCLEAR MEDICINE
fascicolo: 6, volume: 14, anno: 2000,
pagine: 405 - 413
SICI:
0914-7187(200012)14:6<405:CSOVSI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULMONARY;
Keywords:
ventilation/perfusion; collagen disease; pulmonary fibrosis; pulmonary hypertension; pulmonary shunt;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Suzuki, K Tokyo Metropolitan Hiro O Hosp, Dept Radiol, Shibuya Ku, 2-34-10Ebisu, Tokyo 1500013, Japan Tokyo Metropolitan Hiro O Hosp 2-34-10 Ebisu Tokyo Japan 1500013
Citazione:
K. Suzuki et al., "Clinical significance of ventilation/perfusion scans in collagen disease patients", ANN NUCL M, 14(6), 2000, pp. 405-413

Abstract

The purpose of this study was to detect disturbances in pulmonary circulation in collagen disease patients by means of a non-invasive technique, Methods: Ventilation/perfusion scans with Xe-133 gas and Tc-99m-macroaggregatedalbumin (MAA) were performed in 109 patients with various collagen diseases. Functional images of V, Vol, Q and V/Q ratio were obtained at total lungcapacity. Wash-out time was calculated from the wash-out curve. Whole bodyscans were performed in 65 patients to evaluate intra-pulmonary shunts. Results: Increased V/Q areas were observed in 74 patients (67.9%), suggestingsome impairment of pulmonary perfusion. Decreased perfusion, probably due to vasculitis or intravascular microcoagulation, was observed often, even in patients without pulmonary fibrosis. Shunt ratios over 10% were observed in 8 of the 65 patients (12.3%), indicating formation of PA-PV shunts secondary to peripheral vascular impairment. Wash-out time was prolonged in 37 patients (33.9%), shortened in 18 (16.5%), and within the normal range in 54(49.6%). The prolonged and normal wash-out times in the patients with pulmonary fibrosis may represent obstructive changes in the small airways superimposed on the fibrosis. Conclusion: Ventilation/perfusion scans are a veryuseful tool for evaluating collagen lune diseases, and they might contribute to treatment decisions for the patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 07:48:14