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Titolo:
Diffusion-weighted MR imaging for differentiation of benign fracture edemaand tumor infiltration of the vertebral body
Autore:
Spuentrup, E; Buecker, A; Adam, G; van Vaals, JJ; Guenther, RW;
Indirizzi:
Beth Israel Deaconess Med Ctr, Div Cardiovasc Cardiac MRI, Boston, MA 02215 USA Beth Israel Deaconess Med Ctr Boston MA USA 02215 I, Boston, MA 02215 USA Philips Med Syst, NL-5680 DA Best, Netherlands Philips Med Syst Best Netherlands NL-5680 DA L-5680 DA Best, Netherlands
Titolo Testata:
AMERICAN JOURNAL OF ROENTGENOLOGY
fascicolo: 2, volume: 176, anno: 2001,
pagine: 351 - 358
SICI:
0361-803X(200102)176:2<351:DMIFDO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
PATHOLOGICAL COMPRESSION FRACTURES; CHEMICAL-SHIFT; ECHO; OSTEOPOROSIS; APPEARANCE; ARTIFACTS; PERFUSION; IMAGES; WATER; MODEL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Spuentrup, E Aachen Tech Univ, Dept Diagnost Radiol, Pauwelsstr 30, D-52057 Aachen, Germany Aachen Tech Univ Pauwelsstr 30 Aachen Germany D-52057 ermany
Citazione:
E. Spuentrup et al., "Diffusion-weighted MR imaging for differentiation of benign fracture edemaand tumor infiltration of the vertebral body", AM J ROENTG, 176(2), 2001, pp. 351-358

Abstract

OBJECTIVE. The aim of this study was to investigate diffusion-weighted MR imaging for differentiation of benign fracture edema and tumor infiltrationwith and without accompanying fracture. SUBJECTS AND METHODS. In 10 volunteers, diffusion-weighted spin-echo, fat-suppressed spin-echo, and stimulated-echo sequences were optimized on a clinical 1.5-T scanner. In 34 patients, MR imaging with and without diffusion-sensitizing gradients (b = 598 sec/mm(2) in spin-echo and fat-suppressed spin-echo, b = 360 sec/mm(2) in stimulated-echo) was performed. Thirty-five lesions were analyzed, with 18 caused by acute (less than or equal to 10 days old) osteoporotic or traumatic fractures and 17 caused by untreated malignant vertebral infiltration including nine fractures. Signal attenuation indiffusion-weighted images and contrast-to-noise ratio were calculated. Thediffusion-weighted images were analyzed by two radiologists. RESULTS. Images from three of 34 patients were excluded because of motion artifact. In osteoporotic and traumatic fractures, a strong signal attenuation of bone marrow edema was seen. In contrast to this, malignant-tumor infiltration caused only minor signal attenuation (p < 0.05), independent of accompanying pathologic fracture, All sequences showed identical changes of signal intensities. In four patients, initial diagnosis was changed by the findings in the diffusion-weighted images,CONCLUSION. Diffusion-weighted spin-echo, fat-suppressed spin-echo, and stimulated-echo sequences are equally suitable for imaging of the spine. Calculation of signal attenuation and observation of signal characteristics allowed differentiation of benign fracture edema and tumor infiltration and provided excellent distinction between benign and malignant vertebral fractures in our series.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:44:12