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Titolo:
Dietary micronutrients/antioxidants and their relationship with bronchial asthma severity
Autore:
Picado, C; Deulofeu, R; Lleonart, R; Agusti, M; Mullol, J; Qunito, L; Torra, M;
Indirizzi:
Univ Barcelona, Dept Med, Hosp Clin, Serv Pneumol & Allergia Resp, Barcelona, Spain Univ Barcelona Barcelona Spain neumol & Allergia Resp, Barcelona, Spain Univ Barcelona, Dept Med, Hosp Clin, Serv Bioquim Clin, Barcelona, Spain Univ Barcelona Barcelona Spain lin, Serv Bioquim Clin, Barcelona, Spain Univ Barcelona, Dept Med, Hosp Clin, Inst Invest Biomed August Pi & Sunyer, Barcelona, Spain Univ Barcelona Barcelona Spain med August Pi & Sunyer, Barcelona, Spain Univ Barcelona, Dept Med, Hosp Clin, Serv Toxicol, Barcelona, Spain Univ Barcelona Barcelona Spain osp Clin, Serv Toxicol, Barcelona, Spain
Titolo Testata:
ALLERGY
fascicolo: 1, volume: 56, anno: 2001,
pagine: 43 - 49
SICI:
0105-4538(200101)56:1<43:DMATRW>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUTATHIONE-PEROXIDASE ACTIVITY; NUTRITION-EXAMINATION-SURVEY; LUNG-FUNCTION; VITAMIN-C; LIQUID-CHROMATOGRAPHY; REDUCED SELENIUM; NATIONAL-HEALTH; WHOLE-BLOOD; POPULATION; MAGNESIUM;
Keywords:
antioxidants; bronchial asthma; diet; micronutrients;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Picado, C Hosp Clin, Serv Pneumol, Villarroel 170, E-08036 Barcelona, Spain Hosp Clin Villarroel 170 Barcelona Spain E-08036 rcelona, Spain
Citazione:
C. Picado et al., "Dietary micronutrients/antioxidants and their relationship with bronchial asthma severity", ALLERGY, 56(1), 2001, pp. 43-49

Abstract

Background: Because little is known about micronutrient/antioxidant intakeand asthma severity, we investigated dietary intake and plasma/serum levels of micronutrients/antioxidants in a group of asthma patients with variousdegrees of severity, and compared the results with healthy subjects. Methods: A case control study was carried out on 118 asthma patients and 121 healthy subjects. The severity of the disease was classified by divisionof patients into four groups. Normal dietary micronutrient/antioxidant intake was estimated fi um a food frequency questionnaire. Plasma/serum levelsof vitamins C, E, and A, selenium, magnesium, zinc, and platelet glutathione peroxidase (GSH-Px) activity were also determined. Results: No differences in daily micronutrient/antioxidant intake were seen between patients and healthy subjects. The severity of the disease showedno significant relationship with micronutrient/antioxidant intake. There were no differences in plasma/serum levels in any of the micronutrients/antioxidants between healthy subjects and asthmatics. Nor were any differences found between asthma groups in severity in the biochemical measures, exceptin platelet GSH-Px; activity, which was significantly lower in the most severe groups. Conclusions: In this study, we found no evidence of any association between micronutrient/antioxidant intake or plasma/serum levels of micronutrients/ antioxidants and asthma. Reduction of platelet GSH-Px activity in the most severe patients suggests that these patients have a diminished capacity to restore part of the antioxidant defences.

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Documento generato il 05/04/20 alle ore 06:37:47