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Titolo:
Non-invasive assessment of equine bone: An update
Autore:
Lepage, OM; Carstanjen, B; Uebelhart, D;
Indirizzi:
Ecole Natl Vet, Dept Hippique, F-69280 Marcy Etoile, France Ecole Natl Vet Marcy Etoile France F-69280 F-69280 Marcy Etoile, France Univ Liege, Dept Med Interne Grands Animaux, Fac Med Vet, B-4000 Sart, Belgium Univ Liege Sart Belgium B-4000 nimaux, Fac Med Vet, B-4000 Sart, Belgium Univ Zurich Hosp, Dept Rheumatol, CH-8091 Zurich, Switzerland Univ Zurich Hosp Zurich Switzerland CH-8091 CH-8091 Zurich, Switzerland Univ Zurich Hosp, Inst Med Phys, CH-8091 Zurich, Switzerland Univ Zurich Hosp Zurich Switzerland CH-8091 CH-8091 Zurich, Switzerland Rush Presbyterian St Lukes Med Ctr, Dept Biochem, Chicago, IL 60612 USA Rush Presbyterian St Lukes Med Ctr Chicago IL USA 60612 ago, IL 60612 USA
Titolo Testata:
VETERINARY JOURNAL
fascicolo: 1, volume: 161, anno: 2001,
pagine: 10 - 22
SICI:
1090-0233(200101)161:1<10:NAOEBA>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
GAMMA-CARBOXYGLUTAMIC ACID; ALKALINE-PHOSPHATASE ISOENZYMES; SERUM OSTEOCALCIN CONCENTRATION; 3RD METACARPAL BONE; BIOCHEMICAL MARKERS; GLA-PROTEIN; COLLAGEN DEGRADATION; THOROUGHBRED HORSES; ULTRASOUND SPEED; MINERAL-CONTENT;
Keywords:
biochemical markers; bone and connective tissue metabolism; quantitative ultrasonography; horse;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
94
Recensione:
Indirizzi per estratti:
Indirizzo: Lepage, OM Ecole Natl Vet, Dept Hippique, BP 83, F-69280 Marcy Etoile, France Ecole Natl Vet BP 83 Marcy Etoile France F-69280 toile, France
Citazione:
O.M. Lepage et al., "Non-invasive assessment of equine bone: An update", VET J, 161(1), 2001, pp. 10-22

Abstract

This paper summarizes traditional and current methods of non-invasive assessment of bone in the horse. The description and potential clinical utilityof two non-invasive technologies with major development in the last decadeare presented, namely, (1) serum biochemical markers for bone turnover and(2) quantitative ultrasound, Serum biochemical markers of bone formation valid in horses are osteocalcin, carboxy-terminal peptide of type I procollagen and bone-specific alkaline phosphatase. The cross-linked carboxy-terminal telopeptide of type 1 collagen c-telopeptides of type I collagen and total deoxypyridinoline are the serum markers for bone degradation. These markers respond more rapidly to skeletal changes than other bone assessment techniques, but ideally each horse needs to be compared with itself. Quantitative ultrasound is radiation free and is a well-tolerated technique for measuring bone properties in horses. This device allows bone speed of sound measurements at various sites using the axial transmission mode along the cortex and gives information about stiffness, architecture, porosity and bone mass. A combination of different non-invasive assessment techniques is recommended for the evaluation of bone biphasic modelling-remodelling activity and the mineral phase with its architecture. The potential clinical and researchuse of these techniques is considered. (C) 2001 Harcourt Publishers Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 18:36:21