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Titolo:
Study on fluorescent property of degrading products of piperacillin and its analytical application
Autore:
Tang, B; Ma, L; Sun, Y; Wang, HY;
Indirizzi:
Shandong Normal Univ, Dept Chem, Jinan 250014, Peoples R China Shandong Normal Univ Jinan Peoples R China 250014 50014, Peoples R China
Titolo Testata:
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
fascicolo: 2, volume: 57, anno: 2001,
pagine: 217 - 222
SICI:
1386-1425(200102)57:2<217:SOFPOD>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; HUMAN-PLASMA; SERUM; URINE; DERIVATIZATION; PENICILLINS; SAMPLES; INVITRO; HPLC;
Keywords:
antibiotic; sodium piperacillin; degradation; fluorescence analysis; human serum and urine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Tang, B Shandong Normal Univ, Dept Chem, Jinan 250014, Peoples R China Shandong Normal Univ Jinan Peoples R China 250014 eoples R China
Citazione:
B. Tang et al., "Study on fluorescent property of degrading products of piperacillin and its analytical application", SPECT ACT A, 57(2), 2001, pp. 217-222

Abstract

The fluorimetric property of the degrading products of piperacillin has been studied in detail. The studies on degrading pH, degrading time, detection alkalinity and other corresponding analytical parameters of acid degradation have been made. Then fluorometry of piperacillin was established by producing its stable fluorescent products. The detection limit for acid degradation analytical method is 2.34 ng/ml, the linear range is 7.80-4.0 x 10(2)ppb. The analytical sensitivity, precision and stability of degrading products of acid degradation are satisfactory, which has been used for the determination of the trace piperacillin in human serum and urine with satisfactory results. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 22:32:14