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Titolo:
Perioperative intravenous ketoprofen neither prolongs operation time nor delays discharge after adenoidectomy in children
Autore:
Kokki, H; Salonen, A; Nikanne, E;
Indirizzi:
Kuopio Univ Hosp, Dept Anaesthesiol & Intens Care, FIN-70211 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland FIN-70211 are, FIN-70211 Kuopio, Finland Kuopio Univ Hosp, Dept Otorhinolaryngol, FIN-70211 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland FIN-70211 gol, FIN-70211 Kuopio, Finland
Titolo Testata:
PAEDIATRIC ANAESTHESIA
fascicolo: 1, volume: 11, anno: 2001,
pagine: 59 - 64
SICI:
1155-5645(200101)11:1<59:PIKNPO>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMBULATORY SURGERY; IV; SEVOFLURANE; HALOTHANE; ECONOMICS; RECOVERY; PAIN;
Keywords:
analgesics; nonopioid; anti-inflammatory agents; nonsteroidal; ketoprofen; pain : postoperative; child, surgery; daycase; adenoidectomy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Kokki, H Kuopio Univ Hosp, Dept Anaesthesiol & Intens Care, POB 1777, FIN-70211 Kuopio, Finland Kuopio Univ Hosp POB 1777 Kuopio Finland FIN-70211 opio, Finland
Citazione:
H. Kokki et al., "Perioperative intravenous ketoprofen neither prolongs operation time nor delays discharge after adenoidectomy in children", PAEDIATR AN, 11(1), 2001, pp. 59-64

Abstract

Because nonsteroidal anti-inflammatory drugs, such as ketoprofen, prolong bleeding time, their preoperative administration may both prolong operationtime and delay discharge. Therefore, charts of 335 children who had undergone adenoidectomy were evaluated to determine the effect of ketoprofen on operation time (OPERTIME) and length of hospital stay (ACTUAL LOS). The study was conducted in three phases (I-III) which differed from each other in the dose of i.v. ketoprofen, 0.33 mg.kg(-1). All phases were conducted with parallel groups using a prospective, randomized, and double blind design, moreover phases I and In were placebo-controlled. OPERTIMEs were similar between Placebo groups and Ketoprofen groups. The dose of ketoprofen did not affect OPERTIME or ACTUAL LOS. In phase I, ACTUAL LOS was significantly longer in the Placebo group (251 +/- 46 min, mean +/- SD) compared to the Ketoprofen group (225 +/- 44 min, P = 0.006). In conclusion preincisional ketoprofen did not prolong OPERTIME or delay discharge in children undergoing adenoidectomy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 10:02:30