Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Low-potassium and glucose-free dialysis maintains urea but enhances potassium removal
Autore:
Zehnder, C; Gutzwiller, JP; Huber, A; Schindler, C; Schneditz, D;
Indirizzi:
Kantonsspital Aarau, Dept Internal Med, Nephrol & Dialysis Unit, Aarau, Switzerland Kantonsspital Aarau Aarau Switzerland Dialysis Unit, Aarau, Switzerland Kantonsspital Aarau, Ctr Lab Med, Aarau, Switzerland Kantonsspital Aarau Aarau Switzerland , Ctr Lab Med, Aarau, Switzerland Univ Basel, Dept Social & Prevent Med, CH-4003 Basel, Switzerland Univ Basel Basel Switzerland CH-4003 ent Med, CH-4003 Basel, Switzerland Graz Univ, Dept Physiol, A-8010 Graz, Austria Graz Univ Graz Austria A-8010 z Univ, Dept Physiol, A-8010 Graz, Austria
Titolo Testata:
NEPHROLOGY DIALYSIS TRANSPLANTATION
fascicolo: 1, volume: 16, anno: 2001,
pagine: 78 - 84
SICI:
0931-0509(200101)16:1<78:LAGDMU>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC-HEMODIALYSIS; RENAL-FAILURE; PRESCRIPTION; DECREASES; KT/V; LOAD;
Keywords:
glucose-free dialysis; haemodialysis; low-K dialysis; potassium removal; urea removal;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Zehnder, C Fontecilla 441, Santiago, Chile Fontecilla 441 Santiago Chile ontecilla 441, Santiago, Chile
Citazione:
C. Zehnder et al., "Low-potassium and glucose-free dialysis maintains urea but enhances potassium removal", NEPH DIAL T, 16(1), 2001, pp. 78-84

Abstract

Background. The influence of potassium (K) removal on dialysis efficiency as measured by urea elimination is not clear. In this prospective, randomized, crossover study we investigated the magnitude of K removal and its effect on urea (u) elimination during high-flux haemodialysis (HD). Methods. Twelve stable, non-diabetic HD patients were investigated during three one-week standardized HD periods (1.8 m(2) high-flux polysulphone dialyser, treatment time 240 min, Qb = 300 ml/min, Qd = 500 ml/min, dialysate without glucose, bicarbonate 40 mmol/l), using dialysates containing 0 (0K), 1 (1K), and 2 (2K) mmol/l of K. Mass removal of K (M-K) and u (M-U) were measured during the mid-week treatment by partial dialysate collection. Urea reduction rate (URR) and Kt/V were determined. Results. 0K, 1K and 2K treatments were perfectly comparable. Plasma K (PK)continuously declined reaching stable concentrations after 180 min. While OK dialysate removed 117.1 mmol, 80.2 and 63.3 mmol (P < 0.001) were removed by 1K and 2K baths respectively. M-U was not influenced by M-K (r = 0.22)and amounted to 491.1 (0K), 508.6 (1K), and 506.2 (2K)mmol (NS) respectively. Accordingly, urea clearance, URR and Kt/V were constant during OK, 1K and 2K treatments. Conclusions. Potassium-free dialysate significantly enhances potassium elimination. Potassium removal has no influence on urea elimination. High potassium removal, when needed, does not impair dialysis efficiency as measuredby urea kinetics in high-flux, glucose-free, 40 mmol/l bicarbonate HD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:07:25