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Titolo:
Causes of Alzheimer's disease: paracetamol (acetaminophen) today? Amphetamines tomorrow?
Autore:
Jones, GRN;
Titolo Testata:
MEDICAL HYPOTHESES
fascicolo: 1, volume: 56, anno: 2001,
pagine: 121 - 123
SICI:
0306-9877(200101)56:1<121:COADP(>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIPID-PEROXIDATION; ECSTASY; MDMA; DEFICITS; MICE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Jones, GRN 30 Poplar Walk, London SE24 0BU, England 30 Poplar Walk London England SE24 0BU ndon SE24 0BU, England
Citazione:
G.R.N. Jones, "Causes of Alzheimer's disease: paracetamol (acetaminophen) today? Amphetamines tomorrow?", MED HYPOTH, 56(1), 2001, pp. 121-123

Abstract

Phenacetin was implicated as a causative factor in Alzheimer's disease (AD) in 1971. Although the chief metabolite, paracetamol, was earlier identified as responsible for its analgesic and antipyretic properties, a link withsenile plaque formation does not appear to have been previously suspected.in common with paracetamol, so-called recreational drugs (RDs) likewise stimulate free radical activity, and might therefore pose a similar danger interms of causing AD later in life. The case for regarding the brain as an even more delicate and vulnerable structure than currently believed, at risk especially from substances untested in man but of proven neurotoxicity inrodents and nonhuman primates, needs to be taken more seriously than at present. (C) 2001 Harcourt Publishers Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:18:57