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Titolo:
Preoperative functional assessment of auditory cortex in adult cochlear implant users
Autore:
Roland, PS; Tobey, EA; Devous, MD;
Indirizzi:
Univ Texas, SW Med Ctr, Dept Otolaryngol, Dallas, TX 75390 USA Univ TexasDallas TX USA 75390 tr, Dept Otolaryngol, Dallas, TX 75390 USA Univ Texas, SW Med Ctr, Nucl Med Ctr, Dept Radiol, Dallas, TX 75390 USA Univ Texas Dallas TX USA 75390 Med Ctr, Dept Radiol, Dallas, TX 75390 USA Univ Texas, Callier Ctr Commun Disorders, Adv Hearing Res Ctr, Dallas, TX 75235 USA Univ Texas Dallas TX USA 75235 Adv Hearing Res Ctr, Dallas, TX 75235 USA
Titolo Testata:
LARYNGOSCOPE
fascicolo: 1, volume: 111, anno: 2001,
pagine: 77 - 83
SICI:
0023-852X(200101)111:1<77:PFAOAC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; STIMULATION;
Keywords:
cochlear implant; speech perception; functional brain imaging; single photon emission computed tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
5
Recensione:
Indirizzi per estratti:
Indirizzo: Roland, PS Univ Texas, SW Med Ctr, Dept Otolaryngol, 5323 Harry Hines Blvd, Dallas, TX 75390 USA Univ Texas 5323 Harry Hines Blvd Dallas TX USA 75390 75390 USA
Citazione:
P.S. Roland et al., "Preoperative functional assessment of auditory cortex in adult cochlear implant users", LARYNGOSCOP, 111(1), 2001, pp. 77-83

Abstract

Objectives: To explore functional neuroanatomical responses to auditory stimulation before and after implantation. Study Design: A prospective study of three cochlear implant candidates (pure-tone averages of 90 dB HL or greater bilaterally and hearing in noise test [HINT] performances of <40%) in which regional cerebral blood flow (rCBF) was assessed using single photon emission computed tomography (SPECT), Methods: Candidates watched a 15-minute videotaped story under four conditions: audio presented monaurally in the right and left ears (aided), audio presented binaurally (aided), and visual-only presentation of the story. Five minutes into each story, 20 to 25 mCi of technetium 99m (Tc-99m) hexamethyl-propyleneamine-oxime (HMPAO) (Ceratec; Nycomed Amersham, Princeton, NJ, U.S.A) was injected over a 30-second period to ensure that subjects were unaware of tracer administration, Subjects were scanned for 20 minutes using a PRISM 3000 gamma camera (Picker International, Cleveland, OH, U.S.A). Data were normalized and do-registered, and subtraction images were compiled. Subtraction images contrasted activation patterns generated under the visual-only control condition to the auditory activation states acquired monaurally and binaurally. Results: Right and left ear monaural stimulation in normal hearing subjects resulted in significant bilateral activation of Brodmann areas 41, 42, 21, 22, and 38, Although substantial intersubject response variability was noted, subjects generelly failed to bilaterally activate these areas under monaural hearing aidpresentations; however, bilateral activation of areas 41 and 22 was noted under binaural presentations. Conclusions: Despite relatively similar hearing losses in each ear, significant differences in preoperative auditory cortex activation were observed between ears, These data suggest that functional brain imaging provides a useful tool for exploring the responsiveness ofthe auditory cortex in cochlear implant candidates.

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Documento generato il 22/01/20 alle ore 12:24:40