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Titolo:
Effects of bupropion sustained-release on sexual functioning and nocturnalerections in healthy men
Autore:
Labbate, LA; Brodrick, PS; Nelson, RP; Lydiard, RB; Arana, GW;
Indirizzi:
Med Univ S Carolina, Dept Psychiat & Behav Sci, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 Sci, Charleston, SC 29425 USA Med Univ S Carolina, Dept Urol, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 rol, Charleston, SC 29425 USA VA Med Ctr, Charleston, SC USA VA Med Ctr Charleston SC USAVA Med Ctr, Charleston, SC USA
Titolo Testata:
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
fascicolo: 1, volume: 21, anno: 2001,
pagine: 99 - 103
SICI:
0271-0749(200102)21:1<99:EOBSOS>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
PENILE TUMESCENCE; DEPRESSED MEN; DYSFUNCTION; ANTIDEPRESSANT; SERTRALINE; IMPOTENCE; RIGIDITY; PAROXETINE; SLEEP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Labbate, LA VAMC 116, 109 Bee St, Charleston, SC 29401 USA VAMC 116 109 Bee St Charleston SC USA 29401 ston, SC 29401 USA
Citazione:
L.A. Labbate et al., "Effects of bupropion sustained-release on sexual functioning and nocturnalerections in healthy men", J CL PSYCH, 21(1), 2001, pp. 99-103

Abstract

Many antidepressants are known to cause adverse sexual effects. Bupropion is an antidepressant with fewer reported adverse sexual effects. Studies ofsexual side effects are often confounded by psychiatric and medical conditions affecting sexual function. In this study, the effects of bupropion on subjective and objective sexual functioning mere measured in healthy men. Thirteen men without psychiatric or medical illness completed a 2-week, placebo-controlled, double-blind, crossover trial of bupropion sustained-release 300 mg/day. Subjects had a 1-week washout period between trials. Sexual function was measured using a validated, self-administered questionnaire andthe RigiScan, an instrument measuring nocturnal penile tumescence and rigidity. No differences were found in self-reported sexual function, number oferections, total erection time, or penile rigidity in subjects taking bupropion compared with those taking placebo or baseline. These findings support that bupropion does not have subjective adverse sexual side effects and does not affect nocturnal erections in healthy men.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 12:46:21