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Titolo:
Autotransfusion during extracorporeal membrane oxygenation
Autore:
Tolksdorf, B; Schmeck, J; Osika, A; Bender, HJ; Quintel, M;
Indirizzi:
Univ Heidelberg, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care Med, D-68167 Mannheim, Germany Univ Heidelberg Mannheim Germany D-68167 Med, D-68167 Mannheim, Germany
Titolo Testata:
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
fascicolo: 12, volume: 23, anno: 2000,
pagine: 840 - 844
SICI:
0391-3988(200012)23:12<840:ADEMO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS-SYNDROME; INFLAMMATORY RESPONSE; BLOOD-TRANSFUSION; CARDIOPULMONARY BYPASS; CARDIAC-SURGERY; LUNG INJURY; CYTOKINES; INFECTION; LEUKOCYTE; DEPLETION;
Keywords:
ECMO; autologous blood transfusion; interleukin; endothelin; coagulation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Tolksdorf, B Univ Heidelberg, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care Med, Theodor Kutzer Ufer 1-3, D-68167 Mannheim, Germany Univ Heidelberg Theodor Kutzer Ufer 1-3 Mannheim Germany D-68167
Citazione:
B. Tolksdorf et al., "Autotransfusion during extracorporeal membrane oxygenation", INT J ARTIF, 23(12), 2000, pp. 840-844

Abstract

To reduce allogeneic blood transfusion requirements during extracorporeal membrane oxygenation (ECMO) we evaluated an autotransfusion device which processes and retransfuses erythrocytes of changed ECMO-systems. We studied 10 elective changes of ECMO-systems in 7 patients. Hemoglobin levels. the amount of retransfused autologous blood and of transfused allogeneic packed red blood cell units were documented within 48 h after the system change andcompared to the measurements obtained from former ECMO-system changes without using any autotransfusion device. We determined the Horrowitz-index, Interleukin 6, 10, TNF-alpha and endothelial concentrations and coagulation parameters during the 48 hours after system change to study the compatibility of this procedure. Allogeneic blood transfusion was reduced from 7 to 2 units of packed red cells using the autotransfusion device. Additionally, nohints of any harmful side effects in these patients was observed.

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Documento generato il 03/08/20 alle ore 15:35:56