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Titolo:
cDNA micro array identification of a gene differentially expressed in adenovirus type 5-versus type 12-transformed cells
Autore:
Vertegaal, ACO; Kuiperij, HB; van Laar, T; Scharnhorst, V; van der Eb, AJ; Zantema, A;
Indirizzi:
Leiden Univ, Med Ctr, MGC Dept Mol Cell Biol, Mol Carcinogenesis Lab, NL-2333 AL Leiden, Netherlands Leiden Univ Leiden Netherlands NL-2333 AL NL-2333 AL Leiden, Netherlands
Titolo Testata:
FEBS LETTERS
fascicolo: 2, volume: 487, anno: 2000,
pagine: 151 - 155
SICI:
0014-5793(200012)487:2<151:CMAIOA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGHLY ONCOGENIC ADENOVIRUS-12; FOLLISTATIN-RELATED PROTEIN; TRANSFORMING REGION; CLONING; DNA; PROMOTER; BINDING;
Keywords:
follistatin-related protein; adenovirus; transformation; cDNA micro array; Wilms tumor; TGF-beta;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Zantema, A Leiden Univ, Med Ctr, MGC Dept Mol Cell Biol, Mol Carcinogenesis Lab, Wassenaarsweg 72, NL-2333 AL Leiden, Netherlands Leiden Univ Wassenaarsweg 72 Leiden Netherlands NL-2333 AL nds
Citazione:
A.C.O. Vertegaal et al., "cDNA micro array identification of a gene differentially expressed in adenovirus type 5-versus type 12-transformed cells", FEBS LETTER, 487(2), 2000, pp. 151-155

Abstract

Proteins encoded by non-oncogenic adenovirus type 5 and oncogenic adenovirus type 12 differentially affect expression of a number of cellular genes. We have used cDNA micro array analysis to identify a cellular gene that is expressed in Ad12- but not in Ad5-transformed cells. This cellular gene masfound to be the gene encoding follistatin-related protein, a TGF-beta inducible gene, Consistently, a constitutive factor binding to Smad binding elements was found in adenovirus type 12-transformed cells. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. Allrights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 22:16:10