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Titolo:
Calcification and degeneration characteristics of the Biocor No-React bovine internal mammary artery (BIMA) - in vivo evaluation in a sheep model
Autore:
Jashari, R; Herijgers, P; Verbeken, E; Van Lommel, A; Nishimura, Y; Racz, R; Flameng, W;
Indirizzi:
Katholieke Univ Leuven, CEHA, B-3000 Louvain, Belgium Katholieke Univ Leuven Louvain Belgium B-3000 A, B-3000 Louvain, Belgium Katholieke Univ Leuven, Dept Pathol, B-3000 Louvain, Belgium Katholieke Univ Leuven Louvain Belgium B-3000 l, B-3000 Louvain, Belgium
Titolo Testata:
CARDIOVASCULAR SURGERY
fascicolo: 1, volume: 9, anno: 2001,
pagine: 44 - 49
SICI:
0967-2109(200102)9:1<44:CADCOT>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
DACRON GRAFT; GLUTARALDEHYDE; VALVES;
Keywords:
experimental; sheep; heterograft; bovine internal mammary artery; degeneration;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Flameng, W Katholieke Univ Leuven, CEHA, Provisorium I,Minderbroedersstr 17, B-3000 Louvain, Belgium Katholieke Univ Leuven Provisorium I,Minderbroedersstr 17 Louvain Belgium B-3000
Citazione:
R. Jashari et al., "Calcification and degeneration characteristics of the Biocor No-React bovine internal mammary artery (BIMA) - in vivo evaluation in a sheep model", CARDIOV SUR, 9(1), 2001, pp. 44-49

Abstract

Objective: The No-React process for biomaterials was suggested to prevent calcification and degeneration. We examined in vivo in a chronic sheep model the performance of a Biocor bovine internal mammary artery (BIMA) graft after No-React processing. Methods:'No-React' processing consists of aldehyde cross-linkage followinga detoxification process with multiple physical variables and incubation with surfactant. Biocor BIMA No-React treated grafts have been interposed inthe carotid artery in seven sheep with a Dacron graft as control. Grafts were explanted after 3 or 6 months and were grossly examined, by X-ray, histology, transmission and scanning electron microscopy, and atomic absorptionspectrophotometry. Results: In the BIMA, good healing was found with a smooth intimal surface, minimal inflammatory reaction, and a well preserved ultrastructure. Calcification increased progressively. In the Dacron grafts, a fibrous covering the inner surface and infiltration with fibroblasts, histiocytes and macrophages was noted. Calcium content was stable,Conclusion: Calcification increased progressively in Biocor BIMA No-React grafts. Minimal inflammatory changes, a smooth inner surface and well preserved ultrastructure were noted. (C) 2001 The International Society for Cardiovascular Surgery. Published by Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 03:18:41