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Titolo:
Mobilization of hematopoietic stem cells
Autore:
Fu, S; Liesveld, J;
Indirizzi:
Univ Rochester, Med Ctr, Dept Internal Med, Hematol Oncol Blood & Marrow Transplant Program, Rochester, NY 14642 USA Univ Rochester Rochester NY USA14642 nt Program, Rochester, NY 14642 USA
Titolo Testata:
BLOOD REVIEWS
fascicolo: 4, volume: 14, anno: 2000,
pagine: 205 - 218
SICI:
0268-960X(200012)14:4<205:MOHSC>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLONY-STIMULATING FACTOR; BLOOD PROGENITOR CELLS; HIGH-DOSE CHEMOTHERAPY; BREAST-CANCER PATIENTS; NON-HODGKINS-LYMPHOMA; FACTOR G-CSF; MULTIPLE-MYELOMA PATIENTS; MARROW CD34(+) CELLS; PLUS G-CSF; PERIPHERAL-BLOOD;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
135
Recensione:
Indirizzi per estratti:
Indirizzo: Liesveld, J Univ Rochester, Med Ctr, Dept Internal Med, Hematol Oncol Blood & Marrow Transplant Program, 601 Elmwood Ave,Box 610, Rochester, NY 14642USA Univ Rochester 601 Elmwood Ave,Box 610 Rochester NY USA 14642
Citazione:
S. Fu e J. Liesveld, "Mobilization of hematopoietic stem cells", BLOOD REV, 14(4), 2000, pp. 205-218

Abstract

Hematopoietic stem cell transplantation has been extensively exploited as a therapeutic and research modality and has revolutionized current patient care. At present, more and more medical centers use peripheral blood progenitor cells for transplantation by mobilizing hematopoietic stem cells from bone marrow to peripheral blood because of potential advantages of peripheral blood stem cell transplantation over bone-marrow transplantation. Different effective mobilization regimens have been developed recently with chemotherapeutic agents, hematopoietic growth factors or their combination. Thisarticle reviews current developments related to hematopoietic stem cell mobilization including the biology of hematopoietic stem cells, strategies for mobilization, management for mobilization failure, mechanisms of mobilization, and side effects during mobilization. Finally the Initiation-Amplification-Emigration-Adaptation Model is proposed to help aid understanding of the mechanisms of hematopoietic stem cell mobilization and to stimulate development of novel and optimal mobilization strategies for patient care. (C)2000 Harcourt Publishers Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 13:18:35