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Titolo:
Bronchial transsection and reanastomosis in pigs with and without bronchial arterial circulation
Autore:
Gade, J; Qvortrup, K; Andersen, CB; Olsen, PS;
Indirizzi:
Copenhagen Univ Hosp, Rigshosp, Dept Cardiothorac Surg, Copenhagen, Denmark Copenhagen Univ Hosp Copenhagen Denmark horac Surg, Copenhagen, Denmark Copenhagen Univ Hosp, Rigshosp, Dept Pathol, Copenhagen, Denmark Copenhagen Univ Hosp Copenhagen Denmark ept Pathol, Copenhagen, Denmark Univ Copenhagen, Panum Inst, Dept Med Anat, Sect B, DK-2200 Copenhagen, Denmark Univ Copenhagen Copenhagen Denmark DK-2200 , DK-2200 Copenhagen, Denmark
Titolo Testata:
ANNALS OF THORACIC SURGERY
fascicolo: 1, volume: 71, anno: 2001,
pagine: 332 - 336
SICI:
0003-4975(200101)71:1<332:BTARIP>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOUBLE-LUNG TRANSPLANTATION; MUCOCILIARY FUNCTION; REVASCULARIZATION; EPITHELIUM; EXPERIENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Gade, J Rigshosp, Dept Thorac Surg, RT 2152,Blegdamsvej 9, DK-2100 Copenhagen, Denmark Rigshosp RT 2152,Blegdamsvej 9 Copenhagen Denmark DK-2100 Denmark
Citazione:
J. Gade et al., "Bronchial transsection and reanastomosis in pigs with and without bronchial arterial circulation", ANN THORAC, 71(1), 2001, pp. 332-336

Abstract

Background. The bronchial artery may be vital to the bronchi and lung parenchyma, but results of lung transplantation have raised doubts. This study was performed to examine the effect of bronchial arterial devascularizationon bronchial morphology after bronchial transsection and reanastomosis. Methods. In 6 pigs (study group), the left main bronchus was transsected, reanastomosed, and devascularized. Six control pigs had the same operation without devascularization. After 1 week, bronchial arterial angiography wasperformed, and specimens were examined with conventional histology and scanning electron microscopy. Results. Histology showed significant changes (inflammation, edema, and fibrosis) in bronchi and lung parenchyma of the study group compared with theunoperated side (p = 0.028) and with the control group (p = 0.050). Scanning electron microscopy showed significant ciliary denudation in the study group's left bronchus compared with the unoperated side (p = 0.043) and withthe control group (p = 0.0071). Conclusions. The loss of cilia of the bronchial epithelium and the occurrence of inflammation, edema, and fibrosis in bronchi and lung parenchyma 1 week postoperatively were significantly related to the absence of the bronchial arterial circulation. (Ann Thorac Surg 2001;71:332-6) (C) 2001 by The Society of Thoracic Surgeons.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 00:28:22