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Titolo:
Effects of glucose supplementation on gastric emptying, blood glucose homeostasis, and appetite in the elderly
Autore:
Beckoff, K; MacIntosh, CG; Chapman, IM; Wishart, JM; Morris, HA; Horowitz, M; Jones, KL;
Indirizzi:
Univ Adelaide, Royal Adelaide Hosp, Dept Med, Adelaide, SA 5000, AustraliaUniv Adelaide Adelaide SA Australia 5000 ed, Adelaide, SA 5000, Australia
Titolo Testata:
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
fascicolo: 2, volume: 280, anno: 2001,
pagine: R570 - R576
SICI:
0363-6119(200102)280:2<R570:EOGSOG>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUCAGON-LIKE PEPTIDE-1; TERM DIETARY SUPPLEMENTATION; DEPENDENT DIABETES-MELLITUS; FOOD-INTAKE; PYLORIC MOTILITY; HEALTHY-SUBJECTS; CHOLECYSTOKININ; TRANSIT; INSULIN; HUMANS;
Keywords:
anorexia of aging; insulin; gastric inhibitory polypeptide; glucagon-like peptide-1; satiety;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Jones, KL Univ Adelaide, Royal Adelaide Hosp, Dept Med, N Terrace, Adelaide, SA 5000, Australia Univ Adelaide N Terrace Adelaide SA Australia 5000 00, Australia
Citazione:
K. Beckoff et al., "Effects of glucose supplementation on gastric emptying, blood glucose homeostasis, and appetite in the elderly", AM J P-REG, 280(2), 2001, pp. R570-R576

Abstract

The aims of this study were to evaluate the effects of dietary glucose supplementation on gastric emptying (GE) of both glucose and fat, postprandialblood glucose homeostasis, and appetite in eight older subjects (4 males, 4 females, aged 65-84 yr). GE of a drink (15 ml olive oil and 33 g glucose dissolved in 185 ml water), blood glucose, insulin, gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), and appetite (diet diaries, visual analog scales, and food intake at a buffet meal consumed after the GE study) were evaluated twice, after 10 days on a standard or a glucose-supplemented diet (70 g glucose 3 times a day). Glucose supplementation accelerated GE of glucose (P < 0.05), but not oil; there was a trend for an increase in GIP (at 15 min, P = 0.06), no change in GLP-1, an earlier insulin peak (P < 0.01), and a subsequent reduction in blood glucose (at 75 min, P, 0.01). Glucose supplementation had no effect on food intake during each diet so that energy intake was greater (P < 0.001) during the glucose-supplemented diet. Appetite ratings and energy intake at the buffet meal were not different. We conclude that, in older subjects, glucose supplementation 1) accelerates GE of glucose, but not fat; 2) modifies postprandial blood glucose homeostasis; and 3) increases energy intake.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/02/20 alle ore 08:18:10