Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The putative beta(4)-adrenergic receptor is a novel state of the beta(1)-adrenergic receptor
Autore:
Granneman, JG;
Indirizzi:
Wayne State Univ, Sch Med, Dept Psychiat & Behav Neurosci, Cellular & ClinNeurobiol Program, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 biol Program, Detroit, MI 48201 USA
Titolo Testata:
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
fascicolo: 2, volume: 280, anno: 2001,
pagine: E199 - E202
SICI:
0193-1849(200102)280:2<E199:TPBRIA>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
BROWN ADIPOSE-TISSUE; BETA(3)-ADRENOCEPTOR KNOCKOUT MICE; BETA-ADRENERGIC-RECEPTOR; CALCITONIN-RECEPTOR; FAT-CELLS; RAT; ADRENOCEPTOR; AGONISTS; ADIPOCYTES; GENE;
Keywords:
LY-362884; propranolol; catecholamines; phenethanolamines; thermogenesis; lipolysis receptor sites and receptor proteins;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Granneman, JG Wayne State Univ, Sch Med, Dept Psychiat & Behav Neurosci, Cellular & ClinNeurobiol Program, 2309 Scott Hall, Detroit, MI 48201 USA Wayne State Univ 2309 Scott Hall Detroit MI USA 48201 01 USA
Citazione:
J.G. Granneman, "The putative beta(4)-adrenergic receptor is a novel state of the beta(1)-adrenergic receptor", AM J P-ENDO, 280(2), 2001, pp. E199-E202

Abstract

The atypical beta (3)-adrenergic receptor (AR) agonist CGP-12177 has been used to define a novel atypical beta -AR subtype, the putative beta (4)-AR. Recent evaluation of recombinant beta -AR subtypes and beta -AR-deficient mice, however, has established the identity of the pharmacological beta (4)-AR as a novel state of the beta (1)-AR protein. The ability of aryloxypropanolamine ligands like CGP-12177 to independently interact with agonist andantagonist states of the beta (1)-AR has important implications regarding receptor classification and the potential development of tissue-specific beta -AR agonists.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 00:12:33