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Titolo:
Aggressive multiple myeloma presenting as mesenteric panniculitis
Autore:
Goh, J; Otridge, B; Brady, H; Breatnach, E; Dervan, P; MacMathuna, P;
Indirizzi:
Mater Misericordiae Hosp, Dept Gastroenterol, Dublin 7, Ireland Mater Misericordiae Hosp Dublin Ireland 7 stroenterol, Dublin 7, Ireland Mater Misericordiae Hosp, Dept Hematol, Dublin 7, Ireland Mater Misericordiae Hosp Dublin Ireland 7 ept Hematol, Dublin 7, Ireland Mater Misericordiae Hosp, Dept Radiol, Dublin 7, Ireland Mater Misericordiae Hosp Dublin Ireland 7 Dept Radiol, Dublin 7, Ireland Mater Misericordiae Hosp, Dept Nephrol, Dublin 7, Ireland Mater Misericordiae Hosp Dublin Ireland 7 ept Nephrol, Dublin 7, Ireland Mater Misericordiae Hosp, Dept Histopathol, Dublin 7, Ireland Mater Misericordiae Hosp Dublin Ireland 7 Histopathol, Dublin 7, Ireland Univ Coll Dublin, Dublin 2, Ireland Univ Coll Dublin Dublin Ireland 2Univ Coll Dublin, Dublin 2, Ireland
Titolo Testata:
AMERICAN JOURNAL OF GASTROENTEROLOGY
fascicolo: 1, volume: 96, anno: 2001,
pagine: 238 - 241
SICI:
0002-9270(200101)96:1<238:AMMPAM>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
RETRACTILE MESENTERITIS; SCLEROSING MESENTERITIS; COLON;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: MacMathuna, P Mater Misericordiae Hosp, Dept Gastroenterol, Eccles St, Dublin 7, Ireland Mater Misericordiae Hosp Eccles St Dublin Ireland 7 Ireland
Citazione:
J. Goh et al., "Aggressive multiple myeloma presenting as mesenteric panniculitis", AM J GASTRO, 96(1), 2001, pp. 238-241

Abstract

Mesenteric panniculitis is a rare disease of the bowel mesentery, characterized by tumor-like infiltration by chronic inflammatory cells, fat necrosis, and fibrosis. Reported cases cited clinical presentation ranging from abdominal pain to fever of unknown origin, the majority of which were idiopathic and associated with a benign prognosis. We report the case of a 43-yr-old male who presented with malaise, weight loss, microcytic anemia, and a high erythrocyte sedimentation rate. Radiographic and histological investigations revealed typical features of mesenteric panniculitis. Initial treatment with high-dose oral prednisolone led to rapid and complete resolution ofsymptomatology, radiographic, and laboratory anomalies. Within 6 months, the patient presented again with anemia, renal failure, and hypercalcemia. Adiagnosis of IgA kappa chain myeloma was made. Despite chemotherapy and restoration of normocalcemia, he died from refractory pulmonary edema. This is the first report of a hematological malignancy initially presenting with features of mesenteric panniculitis culminating in an aggressive course anda fatal outcome. (Am J Gastroenterol 2001;96:238-241. (C) 2001 by Am. Coll. of Gastroenterology).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 05:17:01