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Titolo:
Dietary instead of pharmacological management to counter the adverse effects of physiological adaptations to space flight
Autore:
Fettman, MJ;
Indirizzi:
Colorado State Univ, Dept Pathol, Coll Vet Med & Biomed Sci, Ft Collins, CO 80523 USA Colorado State Univ Ft Collins CO USA 80523 Sci, Ft Collins, CO 80523 USA
Titolo Testata:
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
fascicolo: 2-3, volume: 441, anno: 2000, supplemento:, S
pagine: R15 - R20
SICI:
0031-6768(2000)441:2-3<R15:DIOPMT>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY CALCIUM EXCRETION; ACID-BASE STATUS; POSTMENOPAUSAL WOMEN; POTASSIUM BICARBONATE; AMMONIUM-CHLORIDE; SODIUM-BICARBONATE; EGGSHELL QUALITY; MINERAL BALANCE; CARBON-DIOXIDE; HEALTHY-ADULTS;
Keywords:
dietary cation-anion balance; dietary sodium; potassium bicarbonate; potassium citrate; space flight;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Fettman, MJ Colorado State Univ, Dept Pathol, Coll Vet Med & Biomed Sci, Ft Collins, CO 80523 USA Colorado State Univ Ft Collins CO USA 80523 ins, CO 80523 USA
Citazione:
M.J. Fettman, "Dietary instead of pharmacological management to counter the adverse effects of physiological adaptations to space flight", PFLUG ARCH, 441(2-3), 2000, pp. R15-R20

Abstract

The development of pharmacological countermeasures to the adverse effects of physiological adaptation to microgravity has received relatively more attention than alternatives such as dietary management. The manipulation of dietary cation-anion balance, and its subsequent effects on acid-base metabolism, have been routinely used for some time in managing domestic animal health. More recently, dietary intake by humans of alkalinizing potassium salts has been demonstrated to exert profound beneficial effects on calcium balance, bone mineralization, predisposition to calcium oxalate nephrolithiasis, and overall nitrogen balance. Dietary sodium restriction has also been shown to improve calcium balance, bone mineralization, and the effectiveness of neurohumoral defenses against orthostatic hypotension. It is proposed that these simple alterations in the astronauts' diets may be easily implemented to lessen the adverse effects of physiological adaptations to space flight, and to enhance or even replace prescribed pharmacological counter-measures.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 19:53:34