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Titolo:
Quantification of proteinuria in children using the urinary protein-osmolality ratio
Autore:
Kim, HS; Cheon, HW; Choe, JH; Yoo, KH; Hong, YS; Lee, JW; Kim, SK;
Indirizzi:
Korea Univ, Guro Hosp, Dept Pediat, Seoul 152703, South Korea Korea Univ Seoul South Korea 152703 pt Pediat, Seoul 152703, South Korea
Titolo Testata:
PEDIATRIC NEPHROLOGY
fascicolo: 1, volume: 16, anno: 2001,
pagine: 73 - 76
SICI:
0931-041X(200101)16:1<73:QOPICU>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIABETIC NEPHROPATHY; CREATININE RATIOS; EXCRETION; SAMPLES; QUANTITATION;
Keywords:
proteinuria; osmolality; ratio; children;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Yoo, KH Korea Univ, Guro Hosp, Dept Pediat, 80 Guro Dong, Seoul 152703, South Korea Korea Univ 80 Guro Dong Seoul South Korea 152703 703, South Korea
Citazione:
H.S. Kim et al., "Quantification of proteinuria in children using the urinary protein-osmolality ratio", PED NEPHROL, 16(1), 2001, pp. 73-76

Abstract

A prospective study was conducted to determine the correlation of early morning urinary protein/osmolality ratio (mg/l/mosmol/kg) with 24-h urinary protein excretion (mg/m(2)/day). Study patients consisted of 53 children (aged 1 month to 15 years). Early morning urine samples and 24-h urine sampleswere collected and analyzed. In group 1 (children without proteinuria), early morning urinary protein/creatinine ratio (Uprot/Ucr, mg/mg) was 0.061+/-0.011 and the protein/osmolality ratio (Uprot/Uosm, mg/l/mosmol/kg) was 0.073+/-0.014. Twenty-four hour urinary protein excretion in group I had no significant correlation with Uprot/Ucr or Uprot/Uosm. In group II (children with proteinuria), Uprot/Ucr was 5.78+/-1.10 and Uprot/Uosm was 4.42+/-1.34. Twenty-four hour urinary protein excretion in group 2 was 1483.6+/-303.7 mg/m2/day and its correlation with both Uprot/Uosm and Uprot/Ucr was highlysignificant (II 0.87, P<0.001 and r=0.88, P<0.001, respectively). The accepted nephrotic level of proteinuria of 40 mg/m(2)/h coincides with a Uprot/Uosm ratio of 1.9. In conclusion, early morning urinary Uprot/Uosm is a simple and potentially useful test for 24-h urinary protein excretion, and possibly could be used safely for the assessment of the degree of proteinuria in children.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 22:28:08