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Titolo:
Transport of nutrients across the choroid plexus
Autore:
Segal, MB;
Indirizzi:
Univ London Kings Coll, St Thomas Hosp, Guys Kings & St Thomas Sch Biomed Sci, London SE1 7EH, England Univ London Kings Coll London England SE1 7EH i, London SE1 7EH, England
Titolo Testata:
MICROSCOPY RESEARCH AND TECHNIQUE
fascicolo: 1, volume: 52, anno: 2001,
pagine: 38 - 48
SICI:
1059-910X(20010101)52:1<38:TONATC>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-CEREBROSPINAL-FLUID; CENTRAL-NERVOUS-SYSTEM; EPITHELIAL-CELLS; BRAIN-BARRIER; THYROXINE TRANSPORT; ACTIVE-TRANSPORT; SATURABLE UPTAKE; AMINO-ACIDS; RAT; SHEEP;
Keywords:
choroid plexus; cerebrospinal fluid; transport systems;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
92
Recensione:
Indirizzi per estratti:
Indirizzo: Segal, MB Univ London Kings Coll, St Thomas Hosp, Guys Kings & St Thomas Sch Biomed Sci, London SE1 7EH, England Univ London Kings Coll London England SE1 7EH SE1 7EH, England
Citazione:
M.B. Segal, "Transport of nutrients across the choroid plexus", MICROSC RES, 52(1), 2001, pp. 38-48

Abstract

A brief outline is given first of the early history of the ventricles and the strange ideas of their functions from Galen to the enlightenment of theRenaissance with the work of Versalius. This is follow ed by a descriptionof the histology of the choroid plexuses (CP) and discussion on the functions of the choroid plexus and on the composition of cerebrospinal fluid (CSF). The methods of measuring the rate of secretion of CSF will be outlined and the possible nutritive functions of the choroid plexuses will be considered. The role of the choroid plexuses in the control of the concentration of glucose and amino acids in CSF will be compared with data from in vitro experiments to that from the isolated vascularly perfused choroid plexuses. The handling of peptides and proteins by the CP and the synthesis of thesemolecules by this tissue is then discussed and the effects of lead on the synthesis of transthyretin by this tissue, Finally, reference will be made to the extensive neuro-endocrine role of the CP and efflux systems across the tissue for lipid soluble molecules. (C) 2001 Wiley Liss. inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 02:52:33