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Titolo:
Reflectance spectroscopy for in vivo characterization of ovarian tissue
Autore:
Utzinger, U; Brewer, M; Silva, E; Gershenson, D; Blast, RC; Follen, M; Richards-Kortum, R;
Indirizzi:
Univ Texas, Biomed Engn Program, Austin, TX 78712 USA Univ Texas Austin TX USA 78712 Biomed Engn Program, Austin, TX 78712 USA Univ Texas, Sch Med, Dept Gynecol, Houston, TX 77030 USA Univ Texas Houston TX USA 77030 Med, Dept Gynecol, Houston, TX 77030 USA Univ Texas, MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA Univ Texas Houston TX USA 77030 Dept Gynecol Oncol, Houston, TX 77030 USA Univ Texas, MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA Univ Texas Houston TX USA 77030 c Ctr, Dept Pathol, Houston, TX 77030 USA Univ Texas, MD Anderson Canc Ctr, Div Med, Houston, TX 77030 USA Univ Texas Houston TX USA 77030 Canc Ctr, Div Med, Houston, TX 77030 USA
Titolo Testata:
LASERS IN SURGERY AND MEDICINE
fascicolo: 1, volume: 28, anno: 2001,
pagine: 56 - 66
SICI:
0196-8092(2001)28:1<56:RSFIVC>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
ASYMPTOMATIC POSTMENOPAUSAL WOMEN; DIFFUSE-REFLECTANCE; LIGHT-SCATTERING; CANCER; DIAGNOSIS; CA-125; ULTRASOUND; NEOPLASIA; CARCINOMA; BREAST;
Keywords:
reflectance spectroscopy; ovarian cancer detection;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Richards-Kortum, R Univ Texas, Dept Elect & Comp Engn, Austin, TX 78712 USA Univ Texas Austin TX USA 78712 n, Austin, TX 78712 USA
Citazione:
U. Utzinger et al., "Reflectance spectroscopy for in vivo characterization of ovarian tissue", LASER SURG, 28(1), 2001, pp. 56-66

Abstract

Background and Objective: To explore whether reflectance spectroscopy can differentiate normal ovary, benign neoplasms, and ovarian cancer. Study Design/Materials and Methods: Reflectance spectra (390-600 nm) were measured at three source-detector separations (SDS) in vivo at 64 sites in 16 patients undergoing oophorectomy. Parameters with largest statistical differences were identified. Based an these parameters algorithms were developed and evaluated. Results: Promising parameters were the reflectance intensity from 540 to 580 nm (SDS, 1.1 mm), the slope of the reflectance spectrum from 490 to 520 nm (SDS, 1.1 mm), the slope from 510 to 530 nm (SDS, 2.1 mm), and the slopefrom 510 to 530 (SDS, 3 mm). Average sensitivity and specificity were 86 +/- 6% and 79 +/- 5% to separate normal ovary from benign neoplasms and cancers. Average sensitivity and specificity were 86 +/- 4% and 80 +/- 8% to separate ovarian cancers from benign neoplasms and normal ovary. Conclusion: Reflectance spectroscopy should be further investigated for ovarian cancer screening. Lasers Surg. Med. 28:56-66, 2001 (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:52:50