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Titolo:
Performance characteristics of quantification assays for human immunodeficiency virus type 1 RNA
Autore:
Schmitt, Y;
Indirizzi:
Klinikum Darmstadt, Inst Lab Med, D-64283 Darmstadt, Germany Klinikum Darmstadt Darmstadt Germany D-64283 D-64283 Darmstadt, Germany
Titolo Testata:
JOURNAL OF CLINICAL VIROLOGY
fascicolo: 1-2, volume: 20, anno: 2001,
pagine: 31 - 33
SICI:
1386-6532(200101)20:1-2<31:PCOQAF>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Keywords:
quantification; immunodeficiency; therapy;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
5
Recensione:
Indirizzi per estratti:
Indirizzo: Schmitt, Y Klinikum Darmstadt, Inst Lab Med, Grafenstr 9, D-64283 Darmstadt, Germany Klinikum Darmstadt Grafenstr 9 Darmstadt Germany D-64283 rmany
Citazione:
Y. Schmitt, "Performance characteristics of quantification assays for human immunodeficiency virus type 1 RNA", J CLIN VIRO, 20(1-2), 2001, pp. 31-33

Abstract

Quantification of human immunodeficiency virus type 1 (HIV-1) is useful inobtaining information about the prognosis of patients and monitoring of antiviral therapy. Today, commercial assays based on reverse transcription-polymerase chain reaction (RT-PCR), the branched DNA (bDNA) technology and onnucleic acid sequence-based amplification (NASBA) are available. Clinical relevance of those assays is limited because of relatively poor reproducibility, especially for low copy numbers and unequal amplification dynamics for different genotypes. Better standardisation is most important in order toimprove the reliability of quantitative molecular assays. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:05:40