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Titolo:
Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses
Autore:
Imbriaco, M; Del Vecchio, S; Riccardi, A; Pace, L; Di Salle, F; Di Gennaro, F; Salvatore, M; Sodano, A;
Indirizzi:
Univ Naples Federico II, CNR, Nucl Med Ctr, Naples, Italy Univ Naples Federico II Naples Italy , CNR, Nucl Med Ctr, Naples, Italy Univ Naples Federico II, Dept Biomorphol & Funct Sci, Naples, Italy Univ Naples Federico II Naples Italy morphol & Funct Sci, Naples, Italy
Titolo Testata:
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
fascicolo: 1, volume: 28, anno: 2001,
pagine: 56 - 63
SICI:
0340-6997(200101)28:1<56:SWTVDM>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
GD-DTPA; SESTAMIBI SCINTIMAMMOGRAPHY; CANCER; DIAGNOSIS; LESIONS; METHOXYISOBUTYLISONITRILE; MAMMOGRAPHY; BENIGN; DIFFERENTIATION; MORTALITY;
Keywords:
breast cancer; scintimammography; Tc-99m-MIBI; magnetic resonance imaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Imbriaco, M Via Manzoni 214-0,Parc Flory,Isolato 4,Apt 1, I-80123 Naples, Italy Via Manzoni 214-0,Parc Flory,Isolato 4,Apt 1 Naples Italy I-80123
Citazione:
M. Imbriaco et al., "Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses", EUR J NUCL, 28(1), 2001, pp. 56-63

Abstract

Although mammography remains the technique of choice for the early detection of breast cancer, several imaging techniques, including scintimammography and magnetic resonance imaging (MRI), have recently been proposed as adjuncts for this purpose and included in many diagnostic protocols. This studywas undertaken to assess the clinical accuracy of scintimammography with technetium-99m methoxyisobutylisonitrile (MIBI) and contrast-enhanced MRI inthe detection of primary breast carcinoma in patients with equivocal mammographic findings. Forty-nine patients with a suspicious breast mass detected either by physical examination or by mammography and ultrasound (US) werestudied. All patients underwent scintimammography and dynamic contrast-enhanced MRI 1 week apart. The results of the two techniques were compared andcorrelated to the final diagnoses. Two independent readers reported the scans using a four-point confidence scale. The areas under the receiver operator characteristic (ROC) curves were obtained. Scintimammography showed an accuracy for tumour detection of 84%, with a sensitivity of 80% and a specificity of 88%. MRI showed an accuracy of 86%, with a sensitivity and specificity of 96% and 75%, respectively. Comparison of the two areas under the ROC curves showed no significant differences between MRI, 0.91+/-0.05 (mean+/-SD), and scintimammography, 0.88+/-0.05 (P=0.9). It is concluded that dynamic MRI and scintimammography possess comparable accuracy in the diagnosisof primary breast carcinoma in patients with equivocal mammographic or US findings.

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Documento generato il 29/03/20 alle ore 14:34:36