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Titolo:
Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V)
Autore:
Bialer, M; Johannessen, SI; Kupferberg, HJ; Levy, RH; Loiseau, P; Perucca, E;
Indirizzi:
Hebrew Univ Jerusalem, Sch Pharm, IL-91120 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 -91120 Jerusalem, Israel Hebrew Univ Jerusalem, Fac Med, David R Bloom Ctr Pharm, IL-91120 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 -91120 Jerusalem, Israel Natl Ctr Epilepsy, Sandvika, Norway Natl Ctr Epilepsy Sandvika NorwayNatl Ctr Epilepsy, Sandvika, Norway NINDS, Epilepsy Branch, Bethesda, MD USA NINDS Bethesda MD USANINDS, Epilepsy Branch, Bethesda, MD USA Univ Washington, Dept Pharmaceut & Neurol Surg, Seattle, WA USA Univ Washington Seattle WA USA Pharmaceut & Neurol Surg, Seattle, WA USA Bordeaux Univ, Hosp Pellegrin, Dept Neurol, Bordeaux, France Bordeaux Univ Bordeaux France Pellegrin, Dept Neurol, Bordeaux, France Univ Pavia, Dept Internal Med & Therapeut, Clin Pharmacol Unit, Pavia, Italy Univ Pavia Pavia Italy d & Therapeut, Clin Pharmacol Unit, Pavia, Italy
Titolo Testata:
EPILEPSY RESEARCH
fascicolo: 1, volume: 43, anno: 2001,
pagine: 11 - 58
SICI:
0920-1211(200101)43:1<11:PRONAD>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPLEX PARTIAL SEIZURES; VAGUS NERVE-STIMULATION; ADD-ON THERAPY; REFRACTORY PARTIAL EPILEPSY; NEWLY-DIAGNOSED EPILEPSY; LEVETIRACETAM UCB L059; DOUBLE-BLIND TRIAL; LEFT VAGAL NERVE; INFANTILE SPASMS; LAMOTRIGINE MONOTHERAPY;
Keywords:
antiepileptic drugs; drug development; epilepsy; pharmacology; clinical trials; conference;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
198
Recensione:
Indirizzi per estratti:
Indirizzo: Bialer, M Hebrew Univ Jerusalem, Sch Pharm, IL-91120 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 usalem, Israel
Citazione:
M. Bialer et al., "Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V)", EPILEPSY R, 43(1), 2001, pp. 11-58

Abstract

The Fifth Eilat Conference on New Antiepileptic Drugs (AEDs) took place atthe Dan Hotel, Eilat, Israel, 25-29 June 2000. Basic scientists, clinical pharmacologists and neurologists from 20 countries attended the conference,whose main themes included recognition of unexpected adverse effects, new indications of AEDs, and patient-tailored AED therapy. According to tradition, the central part of the conference was devoted to a review of AEDs in development, as well to updates on AEDs that have been marketed in recent years. This article summarizes the information presented on drugs in preclinical and clinical development, including AWD 131-138, DP-valproate, harkoseride, LY300164, NPS 1776, NW 1015. pregabalin, remacemide, retigabine, rufinamide and valrocemide. The potential value of an innovative strategy, porcine embryonic GABAergic cell transplants, is also discussed. Finally, updates on felbamate, fosphenytoin, gabapentin, lamotrigine, levetiracetam, oxcarbazepine, tiagabine, topiramate, vigabatrin, zonisamide, and the antiepileptic vagal stimulator device are presented. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 00:20:22