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Titolo:
White matter lesions impair initiation of FAS flow
Autore:
Fernaeus, SE; Almkvist, O; Bronge, L; Ostberg, P; Hellstrom, A; Winblad, B; Wahlund, LO;
Indirizzi:
Huddinge Univ Hosp, Karolinska Inst, Dept Clin Neurosci & Family Med, Div Geriatr Med, S-14186 Huddinge, Sweden Huddinge Univ Hosp Huddinge Sweden S-14186 Med, S-14186 Huddinge, Sweden Univ Stockholm, Dept Psychol, S-10691 Stockholm, Sweden Univ Stockholm Stockholm Sweden S-10691 ychol, S-10691 Stockholm, Sweden
Titolo Testata:
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
fascicolo: 1, volume: 12, anno: 2001,
pagine: 52 - 56
SICI:
1420-8008(200101/02)12:1<52:WMLIIO>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
VERBAL FLUENCY; FRONTAL LOBES; DEMENTIA; HYPERINTENSITIES; COGNITION; LANGUAGE; CORTEX; FMRI;
Keywords:
word fluency; frontal lobe; white matter lesions; hyperintensities, periventricular; factor analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Fernaeus, SE Geriatriska Kliniken Huddinge Sjukhus, S-14186 Huddinge, Sweden Geriatriska Kliniken Huddinge Sjukhus Huddinge Sweden S-14186
Citazione:
S.E. Fernaeus et al., "White matter lesions impair initiation of FAS flow", DEMENT G C, 12(1), 2001, pp. 52-56

Abstract

Word fluency performance is known to rely on left frontal cortical regionsand has also been shown to be affected by lesions in the white matter, which may be seen as white matter hyperintensities (WMH) on magnetic resonanceimaging. However, word fluency may be divided into two independent components, initial and late performance, separated in time [J Clin Exp Neuropsychol 1998;20:137-143], The purpose of the current study was to investigate the relationship between the two components of FAS fluency performance and WMH, Patients varying in degree of memory impairment participated: Alzheimer's disease, mild cognitive impairment and subjective memory disorder. WMH were rated with the Scheltens scale in the periventricular and deep subcortical areas, Results demonstrated that WMH in this sam pie of patients may be summarized in two indices according to a principal factor analysis, one anterior factor mainly related to WMH in the frontal lobes and adjacent to ventricles, and a second posterior factor related to parietal and occipital WMH. The initial FAS performance was related to anterior WMH, in particular left frontal or lateral periventricular hyperintensities, whereas the late FAS performance was not related to any index of WMH, Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 21:49:14