Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Enantioselective correlation between retention factor and lipophilicity index in chiral separation on cellulose and amylose tris(3,5-dimethylphenylcarbamate) CSPs in reversed mode: A case study
Autore:
Roussel, C; Bonnet, B; Piederriere, A; Suteu, C;
Indirizzi:
Univ Aix Marseille 3, ENSSPICAM, UMR CNRS 6516, F-13397 Marseille 20, France Univ Aix Marseille 3 Marseille France 20 6, F-13397 Marseille 20, France Chiral Technol Europe, Illkirch, France Chiral Technol Europe Illkirch France Technol Europe, Illkirch, France
Titolo Testata:
CHIRALITY
fascicolo: 1, volume: 13, anno: 2001,
pagine: 56 - 61
SICI:
0899-0042(2001)13:1<56:ECBRFA>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; STATIONARY-PHASE; N-ARYLTHIAZOLIN-2-(THI)-ONE ATROPISOMERS; MICROCRYSTALLINE CELLULOSETRIACETATE; HYDROPHOBIC INTERACTIONS; RECOGNITION MECHANISM; OXYGEN ANALOGS; ENANTIOMERS; PREDICTION; RESOLUTION;
Keywords:
chiral HPLC; substituent effect; chiral recognition; hydrophobic interactions;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Roussel, C Univ Aix Marseille 3, ENSSPICAM, UMR CNRS 6516, F-13397 Marseille 20, France Univ Aix Marseille 3 Marseille France 20 Marseille 20, France
Citazione:
C. Roussel et al., "Enantioselective correlation between retention factor and lipophilicity index in chiral separation on cellulose and amylose tris(3,5-dimethylphenylcarbamate) CSPs in reversed mode: A case study", CHIRALITY, 13(1), 2001, pp. 56-61

Abstract

For a series of alkyl substituted N-arylthiazoline-2 (thi) one atropisomers 1-14, lipophilicity indexes log kw obtained by polycratic RP-HPLC were compared to In k(+)-S and In k(-)-R obtained on CHIRALCEL OD-R-(R) (reversed mode) and CHIRALPAK AD-RH (R) (reversed mode). Linear correlations were obtained in most cases. It appears that the correlation lines for R and S enantiomers may be parallel, convergent, or divergent, accounting for the observed alpha variation in going from methyl to tert-butyl series. Some tentative hypothesis are given as future investigation routes. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 00:41:57