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Titolo:
Patterns of psychopathology and dysfunction in high-risk children of parents with panic disorder and major depression
Autore:
Biederman, J; Faraone, SV; Hirshfeld-Becker, DR; Friedman, D; Robin, JA; Rosenbaum, JF;
Indirizzi:
Massachusetts Gen Hosp, Clin Psychopharmacol Unit, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 col Unit, Boston, MA 02114 USA Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 Psychiat, Boston, MA 02114 USA Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Med, Dept Psychiat, Boston, MA 02115 USA Harvard Inst Psychiat Epidemiol & Genet, Boston, MA USA Harvard Inst Psychiat Epidemiol & Genet Boston MA USA et, Boston, MA USA
Titolo Testata:
AMERICAN JOURNAL OF PSYCHIATRY
fascicolo: 1, volume: 158, anno: 2001,
pagine: 49 - 57
SICI:
0002-953X(200101)158:1<49:POPADI>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENERALIZED ANXIETY DISORDER; EARLY SEPARATION ANXIETY; DIRECT-INTERVIEW FAMILY; SOCIAL PHOBIA; PSYCHIATRIC-DISORDERS; CO-MORBIDITY; AGORAPHOBIA; ADOLESCENTS; COMORBIDITY; ASSOCIATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Biederman, J Massachusetts Gen Hosp, Clin Psychopharmacol Unit, WACC 725,15 Parkman St,Boston, MA 02114 USA Massachusetts Gen Hosp WACC 725,15 Parkman St Boston MA USA 02114
Citazione:
J. Biederman et al., "Patterns of psychopathology and dysfunction in high-risk children of parents with panic disorder and major depression", AM J PSYCHI, 158(1), 2001, pp. 49-57

Abstract

Objective: The purpose of the study was to evaluate 1) whether an underlying familial predisposition is shared by all anxiety disorders or whether specific risks are associated with specific disorders, and 2) whether panic disorder and major depression have a familial link. Method: The study compared four groups of children: 1) offspring of parents with panic disorder and comorbid major depression (N = 179), 2) offspringof parents with panic disorder without comorbid major depression (N = 29),3) offspring of parents with major depression without comorbid panic disorder (N = 59), and 4) offspring of parents with neither panic disorder nor major depression (N = 113). Results: Parental panic disorder, regardless of comorbidity with major depression, was associated with an increased risk for panic disorder and agoraphobia in offspring. Parental major depression, regardless of comorbidity with panic disorder, was associated with increased risks for social phobia, major depression, disruptive behavior disorders, and poorer social functioning in offspring. Both parental panic disorder and parental major depression, individually or comorbidly, were associated with increased risk for separation anxiety disorder and multiple (two or more) anxiety disorders in offspring. Conclusions: These findings confirm and extend previous results documenting significant associations between the presence of panic disorder and majordepression in parents and patterns of psychopathology and dysfunction in their off sp ri ng.

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Documento generato il 28/09/20 alle ore 15:30:04