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Titolo:
Occupational exposure to pesticides and pancreatic cancer
Autore:
Ji, BT; Silverman, DT; Stewart, PA; Blair, A; Swanson, GM; Baris, D; Greenberg, RS; Hayes, RB; Brown, LM; Lillemoe, KD; Schoenberg, JB; Pottern, LM; Schwartz, AG; Hoover, RN;
Indirizzi:
NCI, Epidemiol & Biostat Program, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA NCI Bethesda MD USA 20892 Epidemiol & Genet, NIH, Bethesda, MD 20892 USA Michigan State Univ, Coll Human Med, E Lansing, MI 48824 USA Michigan State Univ E Lansing MI USA 48824 n Med, E Lansing, MI 48824 USA Med Univ S Carolina, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 ina, Charleston, SC 29425 USA Johns Hopkins Sch Med, Dept Surg, Baltimore, MD USA Johns Hopkins Sch MedBaltimore MD USA Med, Dept Surg, Baltimore, MD USA New Jersey State Dept Hlth, Special Epidemiol Program, Trenton, NJ 08625 USA New Jersey State Dept Hlth Trenton NJ USA 08625 am, Trenton, NJ 08625 USA NHLBI, Womens Hlth Initiat, NIH, Bethesda, MD 20892 USA NHLBI Bethesda MDUSA 20892 ens Hlth Initiat, NIH, Bethesda, MD 20892 USA Barbara Ann Karmanos Canc Inst, Detroit, MI USA Barbara Ann Karmanos Canc Inst Detroit MI USA Canc Inst, Detroit, MI USA
Titolo Testata:
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
fascicolo: 1, volume: 39, anno: 2001,
pagine: 92 - 99
SICI:
0271-3586(200101)39:1<92:OETPAP>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK-FACTORS; MANUFACTURING PLANT; UNITED-STATES; MORTALITY; WORKERS; FARMERS; FLORIDA; DEATH; DDT;
Keywords:
case-control study; job-exposure matrix; occupation; pancreatic cancer; pesticides;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Ji, BT NCI, Epidemiol & Biostat Program, Div Canc Epidemiol & Genet, NIH, Execut Plaza S,Room 8120, Bethesda, MD 20892 USA NCI Execut Plaza S,Room 8120 Bethesda MD USA 20892 da, MD 20892 USA
Citazione:
B.T. Ji et al., "Occupational exposure to pesticides and pancreatic cancer", AM J IND M, 39(1), 2001, pp. 92-99

Abstract

Background An increased risk of exposure to pesticides for pancreatic cancer has been suggested in a number of epidemiologic studies. Methods Cases (N = 484), aged 30-79 years, were diagnosed in 1986-1989. Controls (N = 2,095) were a random sample of the general population. Information on usual occupation and potential confounding factors was obtained. A job-exposure matrix (JEM) approach was used to estimate the level of occupational exposure to pesticides. Results A significant trend in risk with increasing exposure level of pesticides was observed, with ORs of 1.3 and 1.4 for low and moderate/high exposure levels, respectively. Excess risks were found for occupational exposure to fungicides (OR = 1.5) and herbicides (OR = 1.6) in the moderate/high level after adjustment for potential confounding factors. An increased risk for insecticide exposure was disappeared after adjustment for fungicide andherbicide exposures. Results of our occupation-based analysis were consistent with those from the JEM-based analysis. Conclusions Our results suggest that pesticides may increase risk of pancreatic cancer and indicate the need for investigations that can evaluate risk by specific chemical exposures. Am. J. Ind. Med. 39:92-99, 2001. Published 2001 Wiley-Liss, Inc.dagger

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Documento generato il 14/07/20 alle ore 01:52:00