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Titolo:
Interneurons unbound
Autore:
McBain, CJ; Fisahn, A;
Indirizzi:
NICHHD, Lab Cellular & Mol Neurophysiol, Bethesda, MD 20892 USA NICHHD Bethesda MD USA 20892 r & Mol Neurophysiol, Bethesda, MD 20892 USA
Titolo Testata:
NATURE REVIEWS NEUROSCIENCE
fascicolo: 1, volume: 2, anno: 2001,
pagine: 11 - 23
SICI:
1471-0048(200101)2:1<11:IU>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIPPOCAMPUS IN-VITRO; POLYPEPTIDE-IMMUNOREACTIVE INTERNEURONS; CA2+-PERMEABLE AMPA RECEPTORS; HIGH-FREQUENCY OSCILLATIONS; CAT VISUAL-CORTEX; RAT HIPPOCAMPUS; PYRAMIDAL NEURONS; INHIBITORY NEURONS; KAINATE RECEPTORS; ACTION-POTENTIALS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
148
Recensione:
Indirizzi per estratti:
Indirizzo: McBain, CJ NICHHD, Lab Cellular & Mol Neurophysiol, Room 5A72,Bldg 49,49 Convent Dr, Bethesda, MD 20892 USA NICHHD Room 5A72,Bldg 49,49 Convent Dr Bethesda MD USA 20892 SA
Citazione:
C.J. McBain e A. Fisahn, "Interneurons unbound", NAT REV NEU, 2(1), 2001, pp. 11-23

Abstract

Local-circuit, gamma -aminobutyric acid-releasing inhibitory interneurons of the hippocampus and cortex have traditionally been considered as the regulators of principal neuron activity - the yin to the excitatory yang. Recent evidence indicates that, in addition to that role, their network connectivity and the properties of their intrinsic voltage-gated currents are finely tuned to permit inhibitory interneurons to generate and control the rhythmic output of large populations of both principal cells and other populations of inhibitory interneurons. This review brings together recently described properties and emerging principles of interneuron function that indicate a much more complex role for these cells than just providers of inhibition.

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Documento generato il 27/01/20 alle ore 17:00:47