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Titolo:
The mitochondrion in apoptosis: how Pandora's box opens
Autore:
Zamzami, N; Kroemer, G;
Indirizzi:
Inst Gustave Roussy, CNRS UMR1599, F-94805 Villejuif, France Inst Gustave Roussy Villejuif France F-94805 , F-94805 Villejuif, France
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 1, volume: 2, anno: 2001,
pagine: 67 - 71
SICI:
1471-0072(200101)2:1<67:TMIAHP>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERMEABILITY TRANSITION PORE; CYTOCHROME-C RELEASE; BAX; BCL-2; PROTEINS;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Kroemer, G Inst Gustave Roussy, CNRS UMR1599, 39 Rue Camille Desmoulins, F-94805 Villejuif, France Inst Gustave Roussy 39 Rue Camille Desmoulins Villejuif France F-94805
Citazione:
N. Zamzami e G. Kroemer, "The mitochondrion in apoptosis: how Pandora's box opens", NAT REV MOL, 2(1), 2001, pp. 67-71

Abstract

There is widespread agreement that mitochondria have a function in apoptosis, but the mechanisms behind their involvement remain controversial. Here we suggest that opening of a multiprotein complex called the mitochondrial permeability transition pore complex is sufficient (and, usually, necessary) for triggering apoptosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 17:54:47