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Titolo:
FULMINANT PNEUMOCYSTIS-CARINII PNEUMONIA IN 4 PATIENTS WITH DERMATOMYOSITIS
Autore:
BACHELEZ H; SCHREMMER B; CADRANEL J; MOULY F; SARFATI C; AGBALIKA F; SCHLEMMER B; MAYAUD CM; DUBERTRET L;
Indirizzi:
HOP ST LOUIS,INST RECH PEAU,1 AVE CLAUDE VELLEFAUX F-75010 PARIS FRANCE HOP ST LOUIS,DERMATOL SERV F-75010 PARIS FRANCE HOP ST LOUIS,SERV REANIMAT MED F-75010 PARIS FRANCE HOP ST LOUIS,SERV DERMATOL 2 F-75010 PARIS FRANCE HOP ST LOUIS,PARASITOL LAB F-75010 PARIS FRANCE HOP ST LOUIS,VIROL LAB F-75010 PARIS FRANCE HOP TENON,SERV PNEUMOL F-75970 PARIS FRANCE
Titolo Testata:
Archives of internal medicine
fascicolo: 13, volume: 157, anno: 1997,
pagine: 1501 - 1503
SICI:
0003-9926(1997)157:13<1501:FPPI4P>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
H. Bachelez et al., "FULMINANT PNEUMOCYSTIS-CARINII PNEUMONIA IN 4 PATIENTS WITH DERMATOMYOSITIS", Archives of internal medicine, 157(13), 1997, pp. 1501-1503

Abstract

Between 1989 and 1996, 4 cases of Pneumocystis carinii pneumonia (PCP) were observed in patients seronegative for the human immunodeficiency virus who were receiving corticosteroid therapy for dermatomyositis in our institution. These cases were considered unusual in light of the short delay of their onset after initiation of immunosuppressive therapy and their fulminant course: 3 of these patients died of PCP occurring during the first month of treatment with prednisone. In all 4 patients lymphopenia was observed before the initiation of corticosteroidtreatment and low CD4 and CD8 cell counts were evident at the time ofPCP. These observations support the view of an increase in both the severity and incidence of PCP in patients without human immunodeficiency virus infection and question the need for a primary prophylaxis in patients with connective tissue diseases receiving high-dose corticosteroid therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 18:21:44