Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Comparison of diffusion, blood oxygenation, and blood volume changes during global ischemia in rats
Autore:
de Crespigny, AJ; Rother, R; Beaulieu, C; Neumann-Haefelin, T; Moseley, ME;
Indirizzi:
Stanford Univ, Dept Radiol, Lucas Ctr, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305 ol, Lucas Ctr, Stanford, CA 94305 USA Univ Hamburg, Neurol Klin, Hamburg, Germany Univ Hamburg Hamburg Germany niv Hamburg, Neurol Klin, Hamburg, Germany Univ Alberta, Dept Biomed Engn, Edmonton, AB, Canada Univ Alberta Edmonton AB Canada , Dept Biomed Engn, Edmonton, AB, Canada
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 1, volume: 45, anno: 2001,
pagine: 10 - 16
SICI:
0740-3194(200101)45:1<10:CODBOA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESONANCE-IMAGING ASSESSMENT; FOCAL CEREBRAL-ISCHEMIA; REVERSIBLE ISCHEMIA; WATER DIFFUSION; CAT BRAIN; MRI; CONTRAST; ECHO; ADC; HYPERGLYCEMIA;
Keywords:
magnetic resonance imaging; cerebral ischemia, global; cerebral blood volume; rats; blood oxygenation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: de Crespigny, AJ Massachusetts Gen Hosp, NMR Ctr, Bldg 149,13th St, Charlestown, MA 02129 USA Massachusetts Gen Hosp Bldg 149,13th St Charlestown MA USA 02129
Citazione:
A.J. de Crespigny et al., "Comparison of diffusion, blood oxygenation, and blood volume changes during global ischemia in rats", MAGN RES M, 45(1), 2001, pp. 10-16

Abstract

Rapid diffusion, blood oxygenation, and blood volume weighted echo planar imaging was used to monitor global cerebral ischemia by cardiac arrest in rats. Serial CBV measurements used intravascular iron oxide contrast media (iron dextran), ADC dropped by 5% within 20 sec of cardiac arrest, then continued to decay slowly until a larger rapid drop after 2 min. After iron oxide injection, the initial 5% drop was not observed. The transverse relaxation rate (R-2, R-2* no iron injection) increased rapidly after cardiac arrest, peaking at about 30 sec, then declining towards baseline. The CBV dropped by about 50% within 20 sec. The initial 5% ADC drop may be a vascular artifact. The rapidity of the CBV-weighted signal drop suggests a flow-mediated contribution to the iron oxide contrast mechanism. Magn Reson Med 45:10-16, 2001. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 23:38:26