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Titolo:
Transient QT interval prolongation with inverted T waves indicates myocardial salvage on dual radionuclide single-photon emission computed tomographyin acute anterior myocardial infarction
Autore:
Obayashi, T; Tokunaga, T; Iiizumi, T; Shiigai, T; Hiroe, M; Marumo, F;
Indirizzi:
Toride Kyodo Gen Hosp, Dept Internal Med, Toride City, Ibaraki 3020022, Japan Toride Kyodo Gen Hosp Toride City Ibaraki Japan 3020022 ki 3020022, Japan Tokyo Med & Dent Univ, Dept Internal Med 2, Tokyo, Japan Tokyo Med & Dent Univ Tokyo Japan iv, Dept Internal Med 2, Tokyo, Japan
Titolo Testata:
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
fascicolo: 1, volume: 65, anno: 2001,
pagine: 7 - 10
SICI:
0047-1828(200101)65:1<7:TQIPWI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
TC-99M PYROPHOSPHATE; ISCHEMIC INJURY; TL-201; CALCIUM;
Keywords:
acute myocardial infarction; dual SPECT (dual single-photon emission computed tomography); scintigraphic overlap; transient QT interval prolongation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Obayashi, T Toride Kyodo Gen Hosp, Dept Internal Med, 2-1-1 Hongo, Toride City, Ibaraki 3020022, Japan Toride Kyodo Gen Hosp 2-1-1 Hongo Toride City Ibaraki Japan 3020022
Citazione:
T. Obayashi et al., "Transient QT interval prolongation with inverted T waves indicates myocardial salvage on dual radionuclide single-photon emission computed tomographyin acute anterior myocardial infarction", JPN CIRC J, 65(1), 2001, pp. 7-10

Abstract

In patients with acute myocardial infarction (AMI), transient QT interval prolongation with a prominent negative T wave is frequently observed in cases of early spontaneous reperfusion and often indicates a good prognosis. Additionally, in nuclear cardiac imaging, technetium-99m/thallium-201 overlap on dual single-photon emission computed tomography (dual SPECT) in AMI patients indicates the presence of viable myocardium and early recanalization. To elucidate the clinical significance of this transient QT interval prolongation, 34 patients (64+/-8 years) admitted within 24h of the onset of anterior AMI were enrolled and classified into 2 groups according to the presence (group A, n=24) or absence (group B, n=10) of scintigraphic overlap onsimultaneous dual SPECT imaging. The maximal QTc interval was 0.59+/-0.06 s in group A and 0.52+/-0.06 s in group B (p<0.01). The peak creatine kinase was lower in group A (2650+/-2160IU/L) than in group B (3490+/-2060IU/L). The left ventricular ejection fraction (LVEF) at discharge was 62+/-11% ingroup A and 49+/-14% in group B (p<0.01). The scintigraphic overlap group had a smaller infarct and better LVEF, which suggests that the QT interval prolongation that appears transiently in the acute phase of AMI indicates scintigraphically the presence of salvaged myocardium.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 03:16:15