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Titolo:
Focal macular ERGs in eyes after removal of macular ILM during macular hole surgery
Autore:
Terasaki, H; Miyake, Y; Nomura, R; Piao, CH; Hori, K; Niwa, T; Kondo, M;
Indirizzi:
Nagoya Univ, Sch Med, Dept Ophthalmol, Showa Ku, Nagoya, Aichi 4668550, Japan Nagoya Univ Nagoya Aichi Japan 4668550 a Ku, Nagoya, Aichi 4668550, Japan
Titolo Testata:
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
fascicolo: 1, volume: 42, anno: 2001,
pagine: 229 - 234
SICI:
0146-0404(200101)42:1<229:FMEIEA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTERNAL-LIMITING MEMBRANE; EPIRETINAL MEMBRANE; INTRAVITREOUS AIR; SURGICAL REMOVAL; ELECTRORETINOGRAMS; DYSTROPHY; HEMORRHAGE; VITRECTOMY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Terasaki, H Nagoya Univ, Sch Med, Dept Ophthalmol, Showa Ku, 65 Tsuruma Cho, Nagoya, Aichi 4668550, Japan Nagoya Univ 65 Tsuruma Cho Nagoya Aichi Japan 4668550 0, Japan
Citazione:
H. Terasaki et al., "Focal macular ERGs in eyes after removal of macular ILM during macular hole surgery", INV OPHTH V, 42(1), 2001, pp. 229-234

Abstract

PURPOSE. The removal of the internal limiting membrane (ILM) for traction maculopathy has recently been advocated. However, it is generally believed that the ILM plays an important role in retinal function, because it is thebasal lamina of the Muller cells that are involved in the generation of the electroretinogram (ERG) b-wave. To date, there has been no objective assessment of retinal function on removing the ILM. In this study, the changes of each component of the focal macular electroretinograms (FMERGs) were investigated in eyes before and after the ILM was removed in the macular area during surgery for idiopathic macular holes (IMHs). METHODS. FMERGs were elicited by a 15 degrees stimulus centered on the fovea and monitored by an infrared fundus camera. FMERGs were recorded from 49eyes of 48 patients with IMHs before and 6 weeks after anatomically successful macular hole surgery. Whether an eye had or did not have the ILM removed was randomly determined. The ILM was removed in 30 eyes (ILM-off group) and was not removed in 19 eyes (ILM-on group). Six months after surgery, the same examination was performed in 27 eyes of the ILM-off group and in 15 eyes of the ILM-on group. The amplitudes and implicit times of the a- and b-waves and the mean amplitudes and implicit times of the first three oscillatory potentials (OP1 to OP3) were compared before and after surgery withinand between the groups. RESULTS. Visual acuity increased significantly after surgery in both groups. In the ILM-on group, the amplitude of the a- and b-waves and the OPs increased significantly 6 months after surgery (P = 0.0093, P = 0.0019, P = 0.0024, respectively, paired t-test). In the ILM-off group, the a-wave amplitude and mean OP amplitudes were significantly larger 6 months after surgery(P = 0.0077, P = 0.0030, respectively, paired t-test). The b-wave amplitude, however, did not change significantly. The percentage increase in the b-wave amplitude 6 months after surgery was significantly higher in the ILM-on group (44.0%) than in the ILM-off group (15.0%; P = 0.037, t-test). CONCLUSIONS. The removal of the ILM had no adverse effect on visual acuity. However, the selective delay of recovery of the FMERG b-wave 6 months after surgery suggests an alteration of retinal physiology in the macular region.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 20:39:25