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Titolo:
Hepatitis C virus infection in a community in the Nile Delta: Risk factorsfor seropositivity
Autore:
Habib, M; Mohamed, MK; Abdel-Aziz, F; Magder, LS; Abdel-Hamid, M; Gamil, F; Madkour, S; Mikhail, NN; Anwar, W; Strickland, GT; Fix, AD; Sallam, I;
Indirizzi:
Univ Maryland, Sch Med, Dept Epidemiol & Prevent Med, Baltimore, MD 21201 USA Univ Maryland Baltimore MD USA 21201 Prevent Med, Baltimore, MD 21201 USA Hepatitis C Prevent Project, Warrac, Egypt Hepatitis C Prevent Project Warrac Egypt Prevent Project, Warrac, Egypt Ctr Field & Appl Res, Warrac, Egypt Ctr Field & Appl Res Warrac EgyptCtr Field & Appl Res, Warrac, Egypt Ain Shams Univ, Fac Med, Cairo, Egypt Ain Shams Univ Cairo EgyptAin Shams Univ, Fac Med, Cairo, Egypt Minia Univ, Fac Med, Minia, Egypt Minia Univ Minia EgyptMinia Univ, Fac Med, Minia, Egypt Assiut Univ, Fac Med, Assiut, Egypt Assiut Univ Assiut EgyptAssiut Univ, Fac Med, Assiut, Egypt Minist Hlth & Populat, Cairo, Egypt Minist Hlth & Populat Cairo EgyptMinist Hlth & Populat, Cairo, Egypt
Titolo Testata:
HEPATOLOGY
fascicolo: 1, volume: 33, anno: 2001,
pagine: 248 - 253
SICI:
0270-9139(200101)33:1<248:HCVIIA>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
EGYPTIAN BLOOD-DONORS; INTRAFAMILIAL TRANSMISSION; HIGH SEROPREVALENCE; PREVALENCE; EPIDEMIOLOGY; ANTIBODY; SPOUSES; TAIWAN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Fix, AD Univ Maryland, Sch Med, Dept Epidemiol & Prevent Med, 660 W Redwood St, Baltimore, MD 21201 USA Univ Maryland 660 W Redwood St Baltimore MD USA 21201 MD 21201 USA
Citazione:
M. Habib et al., "Hepatitis C virus infection in a community in the Nile Delta: Risk factorsfor seropositivity", HEPATOLOGY, 33(1), 2001, pp. 248-253

Abstract

The purpose of this study was to identify risk factors for hepatitis C virus (HCV) infection in a rural village in the Nile Delta with a high prevalence of antibodies to HCV (anti-HCV). One half of the village households were systematically selected, tested for anti-HCV, and interviewed: 973 of 3,999 (24.3%) subjects were anti-HCV-positive (reflecting prior HCV infection but not necessarily current liver disease), with nearly equal prevalence among males and females. Anti-HCV prevalence increased sharply with age amongboth males and females, from 9.3% in those 20 years of age and younger to > 50% in those older than 35, suggesting a cohort effect with reduced transmission in recent years. Multivariate regression was used to estimate independent effects of risk factors on seropositivity. Among those over 20 yearsof age, the following risk factors were significantly associated with seropositivity: age (P < .001); male gender (odds ratio [OR] = 2.5, 95% CI = 1.3-4.7); marriage (OR = 4.1, 2.4-6.9); anti-schistosomiasis injection treatment (OR = 2.0, 1.3-2.9); blood transfusion (OR = 1.8, 1.1-2.9), invasive medical procedure (surgery, catheterization, endoscopy, and/or dialysis) (OR = 1.5, 1.1-1.9); receipt of injections from "informal" health care provider(OR = 1.3, 1.0-1.6); and cesarean section or abortion (OR = 1.4, 1.0-1.9). Exposures not significantly related to anti-HCV positivity in adults included: history of, or active infection with, Schistosoma mansoni, sutures or abscess drainage, goza smoking in a group, and shaving by community barbers. Among those 20 years old or younger, no risk factors were clearly associated with anti-HCV positivity; however, circumcision for boys by informal health care providers was marginally associated with anti-HCV (OR = 1.7, 1.0-3.0). Prevention programs focused primarily on culturally influenced risks in rural Egyptian communities are being implemented and evaluated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/20 alle ore 20:38:57